ID   H7C6B5_CORGT            Unreviewed;        77 AA.
AC   H7C6B5;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Glutaredoxin-like protein NrdH {ECO:0000256|ARBA:ARBA00017945};
GN   Name=nrdH {ECO:0000313|EMBL:AAD41034.1};
GN   ORFNames=APT58_12395 {ECO:0000313|EMBL:AMA00968.1}, AUO95_04965
GN   {ECO:0000313|EMBL:OKX83188.1}, BBD29_12310
GN   {ECO:0000313|EMBL:ANU34471.1};
OS   Corynebacterium glutamicum (Brevibacterium saccharolyticum).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1718 {ECO:0000313|EMBL:AAD41034.1};
RN   [1] {ECO:0000313|EMBL:AAD41034.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 13032 {ECO:0000313|EMBL:AAD41034.1};
RX   PubMed=10439398;
RA   Oehlmann W., Auling G.;
RT   "Ribonucleotide reductase (RNR) of Corynebacterium glutamicum ATCC 13032
RT   -- genetic characterization of a second class IV enzyme.";
RL   Microbiology 145:1595-1604(1999).
RN   [2] {ECO:0007829|PDB:4FIW}
RP   X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS), AND DISULFIDE BONDS.
RX   PubMed=23362277; DOI=10.1074/jbc.m112.392688;
RA   Van Laer K., Dziewulska A.M., Fislage M., Wahni K., Hbeddou A.,
RA   Collet J.F., Versees W., Mateos L.M., Tamu Dufe V., Messens J.;
RT   "NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum
RT   dimerizes at high protein concentration and exclusively receives electrons
RT   from thioredoxin reductase.";
RL   J. Biol. Chem. 288:7942-7955(2013).
RN   [3] {ECO:0000313|EMBL:OKX83188.1, ECO:0000313|Proteomes:UP000186616}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13870 {ECO:0000313|EMBL:OKX83188.1,
RC   ECO:0000313|Proteomes:UP000186616};
RA   Yang J., Yang S.;
RT   "Genome sequence of Corynebacterium glutamicum ATCC13870.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AMA00968.1, ECO:0000313|Proteomes:UP000069326}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA-ARS-USMARC-56828 {ECO:0000313|EMBL:AMA00968.1,
RC   ECO:0000313|Proteomes:UP000069326};
RA   Harhay G.P., Harhay D.M., Smith T.P.L., Bono J.L., Heaton M.P.,
RA   Clawson M.L., Chitko-Mckown C.G., Capik S.F., DeDonder K.D., Apley M.D.,
RA   Lubbers B.V., White B.J., Larson R.L.;
RT   "Annotation of Corynebacterium glutamicum USDA-ARS-USMARC-56828.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|Proteomes:UP000092697}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13869 {ECO:0000313|Proteomes:UP000092697};
RA   Chen X., Yang J., Jiang Y., Yang S., Zhang Y.;
RT   "Genome sequence of Corynebacterium glutamicum ATCC 13869.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|EMBL:ANU34471.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 13869 {ECO:0000313|EMBL:ANU34471.1};
RX   PubMed=28198668;
RA   Yang J., Yang S.;
RT   "Comparative analysis of Corynebacterium glutamicum genomes: a new
RT   perspective for the industrial production of amino acids.";
RL   BMC Genomics 18:940-940(2017).
CC   -!- FUNCTION: Electron transport system for the ribonucleotide reductase
CC       system NrdEF. {ECO:0000256|ARBA:ARBA00002292}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family.
CC       {ECO:0000256|ARBA:ARBA00007787}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF112535; AAD41034.1; -; Genomic_DNA.
DR   EMBL; CP013991; AMA00968.1; -; Genomic_DNA.
DR   EMBL; CP016335; ANU34471.1; -; Genomic_DNA.
DR   EMBL; LOQV01000014; OKX83188.1; -; Genomic_DNA.
DR   RefSeq; WP_003857948.1; NZ_LOQY01000107.1.
DR   PDB; 4FIW; X-ray; 1.50 A; A=1-77.
DR   PDBsum; 4FIW; -.
DR   GeneID; 69622823; -.
DR   KEGG; cgx:SB89_11880; -.
DR   PATRIC; fig|1718.45.peg.2130; -.
DR   OMA; PACVQCD; -.
DR   Proteomes; UP000069326; Chromosome.
DR   Proteomes; UP000092697; Chromosome.
DR   Proteomes; UP000186616; Unassembled WGS sequence.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   CDD; cd02976; NrdH; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR011909; GlrX_NrdH.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   NCBIfam; TIGR02194; GlrX_NrdH; 1.
DR   PANTHER; PTHR34386; GLUTAREDOXIN; 1.
DR   PANTHER; PTHR34386:SF1; GLUTAREDOXIN-LIKE PROTEIN NRDH; 1.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4FIW}.
FT   DOMAIN          3..61
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000259|Pfam:PF00462"
FT   DISULFID        11..14
FT                   /evidence="ECO:0007829|PDB:4FIW"
SQ   SEQUENCE   77 AA;  8431 MW;  E31432F8F2BD8C38 CRC64;
     MAITVYTKPA CVQCNATKKA LDRAGLEYDL VDISLDEEAR EYVLALGYLQ APVVVADGSH
     WSGFRPERIR EMATAAA
//