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Protein

Stress-associated endoplasmic reticulum protein

Gene

SERP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.UniRule annotation

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Stress-associated endoplasmic reticulum proteinUniRule annotation
Gene namesi
Name:SERP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000151778.10
HGNCiHGNC:20607 SERP2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000151778

PTM / Processingi

Proteomic databases

PeptideAtlasiH7C5W3

Expressioni

Gene expression databases

BgeeiENSG00000151778
ExpressionAtlasiH7C5W3 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the RAMP4 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3491 Eukaryota
ENOG411221U LUCA
GeneTreeiENSGT00390000012245
PhylomeDBiH7C5W3

Family and domain databases

InterProiView protein in InterPro
IPR010580 ER_stress-assoc
PANTHERiPTHR15601 PTHR15601, 1 hit
PfamiView protein in Pfam
PF06624 RAMP4, 1 hit

Sequencei

Sequence statusi: Complete.

H7C5W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAKQRIRMA NEKHSKNITQ RGNVAKTLRP QEEKYPVGPW LLALFVFVVC
60 70 80
GSGQPHKLAS PGDCQNFLKV VTSRGSHPTP KTGN
Length:84
Mass (Da):9,283
Last modified:April 18, 2012 - v1
Checksum:iC6BFB210AF006A33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138960 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000493476; ENSP00000435473; ENSG00000151778
UCSCiuc058wsu.1 human

Similar proteinsi

Entry informationi

Entry nameiH7C5W3_HUMAN
AccessioniPrimary (citable) accession number: H7C5W3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health