ID   H7C3Y5_HUMAN            Unreviewed;       184 AA.
AC   H7C3Y5;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Striated muscle enriched protein kinase {ECO:0000313|Ensembl:ENSP00000414549.1};
DE   Flags: Fragment;
GN   Name=SPEG {ECO:0000313|Ensembl:ENSP00000414549.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000414549.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000414549.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000414549.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC053503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   MassIVE; H7C3Y5; -.
DR   PeptideAtlas; H7C3Y5; -.
DR   ProteomicsDB; 45489; -.
DR   Antibodypedia; 11575; 83 antibodies from 23 providers.
DR   Ensembl; ENST00000451076.1; ENSP00000414549.1; ENSG00000072195.15.
DR   UCSC; uc061sxq.1; human.
DR   HGNC; HGNC:16901; SPEG.
DR   VEuPathDB; HostDB:ENSG00000072195; -.
DR   GeneTree; ENSGT00940000161126; -.
DR   HOGENOM; CLU_1478314_0_0_1; -.
DR   ChiTaRS; SPEG; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000072195; Expressed in popliteal artery and 171 other cell types or tissues.
DR   ExpressionAtlas; H7C3Y5; baseline and differential.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:H7C3Y5,
KW   ECO:0007829|PeptideAtlas:H7C3Y5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   REGION          1..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          123..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..184
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000414549.1"
FT   NON_TER         184
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000414549.1"
SQ   SEQUENCE   184 AA;  19227 MW;  2D346F7F53617A87 CRC64;
     XETAEDDISD VQGTQRLELR DDGAFSTPTG TSEEQVSWWG SGQTVLEQEA GSGGGTRRLP
     GSPRQAQATG AGPRHLGVEP LVRASRANLV GASWGSEDSL SVASDLYGSA FSLYRGRALS
     IHVSVPQSGL RREEPDLQPQ LASEAPRRPA QPPPSKSALL PPPSPRVGKR SPPGPPAQPA
     ATPT
//