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Protein

Autophagy-related protein 9

Gene

ATG9A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.UniRule annotation

GO - Biological processi

Keywordsi

Biological processAutophagyUniRule annotation, Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Autophagy-related protein 9UniRule annotation
Gene namesi
Name:ATG9AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000198925.10.
HGNCiHGNC:22408. ATG9A.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198925.

PTM / Processingi

Proteomic databases

MaxQBiH7C1G6.
PaxDbiH7C1G6.
PeptideAtlasiH7C1G6.
PRIDEiH7C1G6.

Expressioni

Gene expression databases

BgeeiENSG00000198925.
ExpressionAtlasiH7C1G6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH7C1G6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG9 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2173. Eukaryota.
ENOG410XQBE. LUCA.
GeneTreeiENSGT00390000014839.

Family and domain databases

InterProiView protein in InterPro
IPR007241. Autophagy-rel_prot_9.
PANTHERiPTHR13038. PTHR13038. 1 hit.
PfamiView protein in Pfam
PF04109. APG9. 1 hit.

Sequencei

Sequence statusi: Fragment.

H7C1G6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LAHIHYMPDH WQGNAHRSQT RDEFAQLFQY KAVFILEELL SPIVTPLILI
60 70 80 90 100
FCLRPRALEI IDFFRNFTVE VVGVGDTCSF AQMDVRQHGH PQWLSAGQTE
110 120 130 140 150
ASVYQQAEDG KTELSLMHFA ITNPGWQPPR ESTAFLGFLK EQVQRDGAAA
160 170 180 190 200
SLAQGGLLPE NALFTSIQSL QSESEPLSLI ANVVAGSSCR GPPLPRDLQG
210 220 230 240
SRHRAEVASA LRSFSPLQPG QAPTGRAHST MTGSGSTSSR PRLN
Length:244
Mass (Da):26,759
Last modified:April 18, 2012 - v1
Checksum:i71F9B0004318F3AA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei244Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068946 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000429920; ENSP00000400234; ENSG00000198925.
UCSCiuc061ssr.1. human.

Similar proteinsi

Entry informationi

Entry nameiH7C1G6_HUMAN
AccessioniPrimary (citable) accession number: H7C1G6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 27, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported