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Protein
Submitted name:

Metalloendopeptidase OMA1, mitochondrial

Gene

OMA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Metalloendopeptidase OMA1, mitochondrialImported
Gene namesi
Name:OMA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000162600.11.
HGNCiHGNC:29661. OMA1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 55HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162600.

PTM / Processingi

Proteomic databases

MaxQBiH7BZX2.
PaxDbiH7BZX2.
PeptideAtlasiH7BZX2.
PRIDEiH7BZX2.

Expressioni

Gene expression databases

BgeeiENSG00000162600.
ExpressionAtlasiH7BZX2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH7BZX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 293Peptidase_M48InterPro annotationAdd BLAST171

Sequence similaritiesi

Belongs to the peptidase M48B family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2661. Eukaryota.
COG0501. LUCA.
GeneTreeiENSGT00390000007027.

Family and domain databases

InterProiView protein in InterPro
IPR001915. Peptidase_M48.
PfamiView protein in Pfam
PF01435. Peptidase_M48. 1 hit.

Sequencei

Sequence statusi: Fragment.

H7BZX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XLFAIIVGRG IRKWWQALPP NKKEVVKENI RKNKWKLFLG LSSFGLLFVV
60 70 80 90 100
FYFTHLEVSP ITGRSKLLLL GKEQFRLLSE LEYEAWMEEF KNDMLTEKDA
110 120 130 140 150
RYLAVKEVLC HLIECNKDVP GISQINWVIH VVDSPIINAF VLPNGQMFVF
160 170 180 190 200
TGFLNSVTDI HQLSFLLGHE IAHAVLGHAA EKAGMVHLLD FLGMIFLTMI
210 220 230 240 250
WAICPRDSLA LLCQWIQSKL QEYMFNRPYS RKLEAEADKI GLLLAAKACA
260 270 280 290 300
DIRASSVFWQ QMEFVDSLHG QPKMPEWLST HPSHGNRVEY LDRLIPQLVR
310 320
EEKFIEQPEQ IAELTLNSFI QNTEICRS
Length:328
Mass (Da):37,823
Last modified:April 18, 2012 - v1
Checksum:i2418A68D4430C394
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109845 Genomic DNA. No translation available.
AL365187 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000421528; ENSP00000391941; ENSG00000162600.
UCSCiuc057gyq.1. human.

Similar proteinsi

Entry informationi

Entry nameiH7BZX2_HUMAN
AccessioniPrimary (citable) accession number: H7BZX2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 27, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported