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Protein

Protein Wnt

Gene

WNT10A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:WNT10AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000135925.8
HGNCiHGNC:13829 WNT10A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135925

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiH7BZB8
PRIDEiH7BZB8

Expressioni

Gene expression databases

BgeeiENSG00000135925
ExpressionAtlasiH7BZB8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH7BZB8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
GeneTreeiENSGT00690000101857

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR013302 Wnt10
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01893 WNT10PROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit

Sequencei

Sequence statusi: Fragment.

H7BZB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XSAPNDILDL RLPPEPVLNA NTVCLTLPGL SRRQMEVCVR HPDVAASAIQ
60 70 80 90 100
GIQIAIHECQ HQFRDQRWNC SSLETRNKIP YESPIFSRGS DGEHAAEVQV
110 120 130 140 150
PRHVRQLPAQ DVLAGDARVP HRGGAAAQPL PPRHAHPAAQ PQRRPAGAGP
160 170 180 190 200
SGGTLAGSGR SRAAPTGQPR RPGLLRKVSR LLRARAAPGL GGHRGPPVQQ
210
EQRRLGWLRQ HV
Length:212
Mass (Da):22,965
Last modified:October 5, 2016 - v8
Checksum:i30623A02F6D4D728
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei212Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073128 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000458582; ENSP00000388812; ENSG00000135925
UCSCiuc061spj.1 human

Entry informationi

Entry nameiH7BZB8_HUMAN
AccessioniPrimary (citable) accession number: H7BZB8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 42 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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