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H7BXP1

- H7BXP1_HUMAN

UniProt

H7BXP1 - H7BXP1_HUMAN

Protein
Submitted name:

NF-kappa-B inhibitor-interacting Ras-like protein 2

Gene

NKIRAS2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW

    GO - Biological processi

    1. GTP catabolic process Source: InterPro
    2. small GTPase mediated signal transduction Source: InterPro

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    NF-kappa-B inhibitor-interacting Ras-like protein 2Imported
    Gene namesi
    Name:NKIRAS2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:17898. NKIRAS2.

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro
    2. membrane Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiH7BXP1.

    Expressioni

    Gene expression databases

    ArrayExpressiH7BXP1.
    BgeeiH7BXP1.

    Structurei

    3D structure databases

    ProteinModelPortaliH7BXP1.
    SMRiH7BXP1. Positions 6-206.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OMAiIEPFVYL.
    PhylomeDBiH7BXP1.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR013684. MIRO-like.
    IPR027417. P-loop_NTPase.
    IPR001806. Small_GTPase.
    IPR020849. Small_GTPase_Ras.
    [Graphical view]
    PANTHERiPTHR24070. PTHR24070. 1 hit.
    PfamiPF08477. Miro. 1 hit.
    PF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SUPFAMiSSF52540. SSF52540. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    H7BXP1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKSCKVVVC GQASVGKTSI LEQLLYGNHV VGSEMIETQE DIYVGSIETD    50
    RGVREQVRFY DTRGLRDGAE LPRHCFSCTD GYVLVYSTDS RESFQRVELL 100
    KKEIDKSKDK KEGLTLPPRL ECSGMITAHC SLNLPRLRWS SCLSPLLRLQ 150
    VTIVVLGNKC DLQEQRRVDP DVAQHWAKSE KVKLWEVSVA DRRSLLEPFV 200
    YLASKMTQPQ SKSAFPLSRK NKGSGSLDG 229
    Length:229
    Mass (Da):25,725
    Last modified:April 18, 2012 - v1
    Checksum:i7D46F3C761443740
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC105024 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000316082; ENSP00000312773; ENSG00000168256.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC105024 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali H7BXP1.
    SMRi H7BXP1. Positions 6-206.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi H7BXP1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000316082 ; ENSP00000312773 ; ENSG00000168256 .

    Organism-specific databases

    HGNCi HGNC:17898. NKIRAS2.
    GenAtlasi Search...

    Phylogenomic databases

    OMAi IEPFVYL.
    PhylomeDBi H7BXP1.

    Miscellaneous databases

    ChiTaRSi NKIRAS2. human.
    NextBioi 35528082.

    Gene expression databases

    ArrayExpressi H7BXP1.
    Bgeei H7BXP1.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR013684. MIRO-like.
    IPR027417. P-loop_NTPase.
    IPR001806. Small_GTPase.
    IPR020849. Small_GTPase_Ras.
    [Graphical view ]
    PANTHERi PTHR24070. PTHR24070. 1 hit.
    Pfami PF08477. Miro. 1 hit.
    PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SUPFAMi SSF52540. SSF52540. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH7BXP1_HUMAN
    AccessioniPrimary (citable) accession number: H7BXP1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3