PPP6R3

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Serine/threonine-protein phosphatase 6 regulatory subunit 3Imported
Gene namesⁱ	Name:PPP6R3Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1173. PPP6R3.

HGNCⁱ

HGNC:1173. PPP6R3.

Subcellular locationⁱ

GO - Cellular componentⁱ

cytosol Source: HPA
nucleoplasm Source: HPA
plasma membrane Source: HPA

Complete GO annotation...

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000110075.

OpenTargetsⁱ

ENSG00000110075.

PTM / Processingⁱ

Proteomic databases

EPDⁱ	H7BXH2.
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	H7BXH2.
PeptideAtlas More...PeptideAtlasⁱ	H7BXH2.
PRIDEⁱ	H7BXH2.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000110075.
ExpressionAtlasⁱ	H7BXH2. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	H7BXH2. 2 interactors.

IntActⁱ

H7BXH2. 2 interactors.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	H7BXH2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000009899.

GeneTreeⁱ

ENSGT00390000009899.

Family and domain databases

Gene3Dⁱ	1.25.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR007587. SAPS.
PANTHERⁱ	PTHR12634. PTHR12634. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04499. SAPS. 2 hits.
SUPFAMⁱ	SSF48371. SSF48371. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

H7BXH2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MFWKFDLHSS SHIDTLLERE DVTLKELMDE EDVLQECKAQ NRKLIEFLLK 
        60         70         80         90        100
AECLEDLVSF IIEEPPQDMD EKIRYKYPNI SCELLTSDVS QMNDRLGEDE 
       110        120        130        140        150
SLLMKLYSFL LNDSPLNPLL ASFFSKVLSI LISRKPEQIV DFLKKKHDFV 
       160        170        180        190        200
DLIIKHIGTS AIMDLLLRLL TCIEPPQPRQ DVLNWLNEEK IIQRLVEIVH 
       210        220        230        240        250
PSQEEDRHSN ASQSLCEIVR LSRDQMLQIQ NSTEPDPLLA TLEKQEIIEQ 
       260        270        280        290        300
LLSNIFHKEK NESAIVSAIQ ILLTLLETRR PTFEGHIEIC PPGMSHSACS 
       310        320        330        340        350
VNKSVLEAIR GRLGSFHELL LEPPKKSVMK TTWGVLDPPV GNTRLNVIRL 
       360        370        380        390        400
ISSLLQTNTS SINGDLMELN SIGVILNMFF KYTWNNFLHT QVEICIALIL 
       410        420        430        440        450
ASPFENTENA TITDQDSTGD NLLLKHLFQK CQLIERILEA WEMNEKKQAE 
       460        470        480        490        500
GGRRHGYMGH LTRIANCIVH STDKGPNSAL VQQLIKDLPD EVRERWETFC 
       510        520        530        540        550
TSSLGETNKR NTVDLFGFND EKFADQDDIG NVSFDRVSDI NFTLNTNESG 
       560        570        580        590        600
NIALFEACCK ERIQQFDDGG SDEEDIWEEK HIAFTPESQR RSSSGSTDSE 
       610        620        630        640        650
ESTDSEEEDG AKQDLFEPSS ANTEDKMEVD LSEPPNWSAN FDVPMETTHG 
       660        670        680        690        700
APLDSVGSDV WSTEEPMPTK ETGWASFSEF TSSLSTKDSL RSNSPVEMET 
       710        720        730        740        750
STEPMDPLTP SAAALAVQPE AAGSVAMEAS SDGEEDAEST DKVTETVMNG 
       760        770        780        790        800
GMKETLSLTV DAKTETAVFK SEEGKLSTSQ DAACKDAEEC PETAEAKCAA 
       810        820 
PRPPSSSPEQ RTGQPSAPGD TSVNGPV

Length:827

Mass (Da):92,409

Last modified:April 18, 2012 - v1

Checksum:ⁱE99B971D4D4E0B1F

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AP000807 Genomic DNA. No translation available. AP001788 Genomic DNA. No translation available. AP003096 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_006718684.1. XM_006718621.2.
UniGeneⁱ	Hs.503022.

Genome annotation databases

Ensemblⁱ	ENST00000265637; ENSP00000265637; ENSG00000110075.
GeneIDⁱ	55291.
UCSC genome browser More...UCSCⁱ	uc001onz.4. human.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AP000807 Genomic DNA. No translation available. AP001788 Genomic DNA. No translation available. AP003096 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_006718684.1. XM_006718621.2.
UniGeneⁱ	Hs.503022.

3D structure databases

ProteinModelPortalⁱ	H7BXH2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	H7BXH2. 2 interactors.

IntActⁱ

H7BXH2. 2 interactors.

Proteomic databases

EPDⁱ	H7BXH2.
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	H7BXH2.
PeptideAtlas More...PeptideAtlasⁱ	H7BXH2.
PRIDEⁱ	H7BXH2.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000265637; ENSP00000265637; ENSG00000110075.
GeneIDⁱ	55291.
UCSC genome browser More...UCSCⁱ	uc001onz.4. human.

Organism-specific databases

CTDⁱ	55291.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1173. PPP6R3.
Open Targets More...OpenTargetsⁱ	ENSG00000110075.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000009899.

GeneTreeⁱ

ENSGT00390000009899.

Miscellaneous databases

ChiTaRSⁱ	PPP6R3. human.
GenomeRNAiⁱ	55291.

Gene expression databases

Bgeeⁱ	ENSG00000110075.
ExpressionAtlasⁱ	H7BXH2. baseline and differential.

Family and domain databases

Gene3Dⁱ	1.25.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR007587. SAPS.
PANTHERⁱ	PTHR12634. PTHR12634. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04499. SAPS. 2 hits.
SUPFAMⁱ	SSF48371. SSF48371. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H7BXH2_HUMAN
Accessionⁱ	H7BXH2Primary (citable) accession number: H7BXH2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 18, 2012
	Last sequence update:	April 18, 2012
	Last modified:	June 7, 2017
	This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - H7BXH2 (H7BXH2_HUMAN)

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Serine/threonine-protein phosphatase 6 regulatory subunit 3

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ