H7BXC3 (H7BXC3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Triosephosphate isomerase RuleBase RU000517
EC=5.3.1.1 RuleBase RU000517

Gene names

Name:

Tpi1 Ensembl ENSMUSP00000125292 MGI 98797

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000125292

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	D-glyceraldehyde 3-phosphate = glycerone phosphate. RuleBase RU000517
Pathway	Carbohydrate biosynthesis; gluconeogenesis. RuleBase RU000517 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. RuleBase RU000517
Sequence similarities	Belongs to the triosephosphate isomerase family. RuleBase RU004162
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000125292

Ontologies

Keywords
Molecular function	Isomerase RuleBase RU000517
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	embryo development Inferred from mutant phenotype PubMed 2693209. Source: MGI gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-UniPathway glucose metabolic process Inferred from direct assay PubMed 2693209. Source: MGI glycolysis Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	triose-phosphate isomerase activity Inferred from direct assay PubMed 15155459PubMed 204065PubMed 2693209PubMed 566476. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H7BXC3 [UniParc]. Last modified April 18, 2012. Version 1. Checksum: 0478BB3AD92AD902	FASTA	167	17,997
	10 20 30 40 50 60 MIKDLGATWV VLGHSERRHV FGESDELIGQ KVSHALAEGL GVIACIGEKL DEREAGITEK 70 80 90 100 110 120 VVFEQTKVIA DNVKDWSKVV LAYEPVWAIG TGKTATPQQA QEVHEKLRGW LKSNVNDGVA 130 140 150 160 QSTRIIYGGS VTGATCKELA SQPDVDGFLV GGASLKPEFV DIINAKQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000125292.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000125292.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC142254 Genomic DNA. No translation available.
3D structure databases
ProteinModelPortal	H7BXC3.
SMR	H7BXC3. Positions 1-167.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000149610; ENSMUSP00000125292; ENSMUSG00000023456.
Organism-specific databases
MGI	MGI:98797. Tpi1.
Phylogenomic databases
GeneTree	ENSGT00390000013354.
Enzyme and pathway databases
UniPathway	UPA00109; UER00189. UPA00138.
Gene expression databases
ArrayExpress	H7BXC3.
Bgee	H7BXC3.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR013785. Aldolase_TIM. IPR000652. Triosephosphate_isomerase. IPR020861. Triosephosphate_isomerase_AS. [Graphical view]
PANTHER	PTHR21139. PTHR21139. 1 hit.
Pfam	PF00121. TIM. 1 hit. [Graphical view]
SUPFAM	SSF51351. Triophos_ismrse. 1 hit.
TIGRFAMs	TIGR00419. tim. 1 hit.
PROSITE	PS00171. TIM_1. 1 hit. PS51440. TIM_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	TPI1. mouse.
NextBio	35562304.
SOURCE	Search...

Entry information

Entry name

H7BXC3_MOUSE

Accession

Primary (citable) accession number: H7BXC3

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2012
Last sequence update:	April 18, 2012
Last modified:	April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)