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H7BX92

- H7BX92_MOUSE

UniProt

H7BX92 - H7BX92_MOUSE

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Protein
Submitted name:

Brain-specific angiogenesis inhibitor 2

Gene

Bai2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: InterPro

GO - Biological processi

  1. negative regulation of angiogenesis Source: InterPro
  2. neuropeptide signaling pathway Source: InterPro
  3. peripheral nervous system development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Brain-specific angiogenesis inhibitor 2Imported
Gene namesi
Name:Bai2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:2451244. Bai2.

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiH7BX92.
ExpressionAtlasiH7BX92. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH7BX92.
SMRiH7BX92. Positions 299-860, 883-1116.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains GPS domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119076.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain-spec_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000203. GPS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 3 hits.
[Graphical view]
PRINTSiPR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 3 hits.
PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H7BX92 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA
60 70 80 90 100
SGCSWTLENP DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP
110 120 130 140 150
GPEEATARAE SEVGRPEEEE EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ
160 170 180 190 200
LCLSAEPSEA PRLLAPAALA FRFVEVLLIN NNNSSQFTCG VLCRWSEECG
210 220 230 240 250
RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN ALVPGGPAPP
260 270 280 290 300
AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTVH
310 320 330 340 350
GVWEEWGSWS LCSRSCGRGS RSRMRTCVPP QHGGKACEGP ELQTKLCSMA
360 370 380 390 400
ACPVEGQWLE WGPWGPCSSS CANGTQQRSR KCSVAGPAWA TCAGALTDTR
410 420 430 440 450
ECSNLDCPAT DGKWGPWNAW SLCSKTCDTG WQRRFRMCQA SGTQGYPCEG
460 470 480 490 500
TGEEVKPCSE KRCPAFHEMC RDEYVMLMTW KRAAAGEIIY NKCPPNASGS
510 520 530 540 550
ASRRCLLSAQ GVAYWGLPSF ARCISHEYRY LYLSLREHLA KGQRMLAGEG
560 570 580 590 600
MSQVVRSLQE LLARRTYYSG DLLFSVDILR NVTDTFKRAT YVPSADDVQR
610 620 630 640 650
FFQVVSFMVD SENKDKWDDA QQVSPGSVHL LRVVEDFIHL VGDALKAFQS
660 670 680 690 700
SLIVTDNLVI SIQREPISAV SSDITFPMRG RRGMKDWVRH SEDRLFLPKE
710 720 730 740 750
VLSLSSPGKP ATPGAATAGS PGRGRGPGTV PPGPGHAHQR LLPADPEESS
760 770 780 790 800
SYFVIGAVLY RTLGLILPPP RPPLAVTSRV MTVTVRPPTQ PPAEPLITVE
810 820 830 840 850
LSYIINGTTD PHCASWDYSR ADTNSGDWNT ESCQTLETQA AHTRCQCQHL
860 870 880 890 900
STFAVLAQPP KDLTLELAGA PSVPLVIGCA VSCMALLTLL AIYAAFWRFI
910 920 930 940 950
KSERSIILLN FCLSILASNI LILVGQSRVL SKGVCTMTAA FLHFFFLSSF
960 970 980 990 1000
CWVLTEAWQS YLAVIGRMRT RLVRKRFLCL GWGLPALVVA VSVGFTRTKG
1010 1020 1030 1040 1050
YGTSSYCWLS LEGGLLYAFV GPAAVIVLVN MLIGIIVFNK LMARDGVSDK
1060 1070 1080 1090 1100
SKKQRAGASL WSSCVVLPLL ALTWMSAVLA MTDRRSVLFQ ALFAVFNSAQ
1110 1120 1130 1140 1150
GFVITAVHCF LRREVQDVVK CQMGVCRADE SEDSPDSCKN GQLQILSDFE
1160 1170 1180 1190 1200
KDVDLACQTV LFKEVNTCNP STITGTLSRL SLDEDEEPKS CLVGPEGGLS
1210 1220 1230 1240 1250
FSPLPGNILV PMAASPGLGE PPPPQETNPV YMCGEGGLRQ LDLTWIRQSE
1260 1270 1280 1290 1300
PGSEGDYMVL PRRTLSLQPG GGGTAGEEAP RARPEGTPRR AAKTVAHTEG
1310 1320 1330 1340 1350
YPSFLSVEHS GLGLGPAYGS LQNPYGMTFQ PPPPTPSARQ VPEPGERSRT
1360 1370 1380 1390 1400
MPRTVPGSTM KLGSLERKKL RYSDLDFEKV MHTRKRHSEL YHELNQKFHT
1410 1420 1430 1440 1450
FDRYRSQSSA KVRWMRGCNR LALLLSQEKP SPPGGRPGLS QHRRHQSWST
1460 1470 1480
FKSMTLGSLP PKPRERLALH RTAAWEPTEP PDGDFQTEV
Length:1,489
Mass (Da):162,633
Last modified:April 18, 2012 - v1
Checksum:iAEB78464AFD52F2D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL626774 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000106018; ENSMUSP00000101639; ENSMUSG00000028782.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL626774 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali H7BX92.
SMRi H7BX92. Positions 299-860, 883-1116.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000106018 ; ENSMUSP00000101639 ; ENSMUSG00000028782 .

Organism-specific databases

MGIi MGI:2451244. Bai2.

Phylogenomic databases

GeneTreei ENSGT00760000119076.

Miscellaneous databases

ChiTaRSi BAI2. mouse.
NextBioi 35562293.
SOURCEi Search...

Gene expression databases

Bgeei H7BX92.
ExpressionAtlasi H7BX92. baseline and differential.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain-spec_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000203. GPS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view ]
Pfami PF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 3 hits.
[Graphical view ]
PRINTSi PR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTi SM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view ]
SUPFAMi SSF82895. SSF82895. 3 hits.
PROSITEi PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
    Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
    J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH7BX92_MOUSE
AccessioniPrimary (citable) accession number: H7BX92
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3