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Protein
Submitted name:

Adhesion G protein-coupled receptor B2

Gene

Adgrb2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor B2Imported
Gene namesi
Name:Adgrb2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2451244. Adgrb2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei875 – 89622HelicalSequence analysisAdd
BLAST
Transmembranei908 – 92922HelicalSequence analysisAdd
BLAST
Transmembranei941 – 96525HelicalSequence analysisAdd
BLAST
Transmembranei977 – 99519HelicalSequence analysisAdd
BLAST
Transmembranei1015 – 103824HelicalSequence analysisAdd
BLAST
Transmembranei1059 – 108123HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 14891469Sequence analysisPRO_5005918043Add
BLAST

Expressioni

Gene expression databases

BgeeiH7BX92.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini457 – 52771G_PROTEIN_RECEP_F2_3InterPro annotationAdd
BLAST
Domaini810 – 86253GPSInterPro annotationAdd
BLAST
Domaini871 – 1112242G_PROTEIN_RECEP_F2_4InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains GPS domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00820000126962.

Family and domain databases

InterProiIPR032471. GAIN_dom_N.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
IPR000884. TSP1_rpt.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF16489. GAIN. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 3 hits.
[Graphical view]
PRINTSiPR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 3 hits.
PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H7BX92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA
60 70 80 90 100
SGCSWTLENP DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP
110 120 130 140 150
GPEEATARAE SEVGRPEEEE EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ
160 170 180 190 200
LCLSAEPSEA PRLLAPAALA FRFVEVLLIN NNNSSQFTCG VLCRWSEECG
210 220 230 240 250
RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN ALVPGGPAPP
260 270 280 290 300
AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTVH
310 320 330 340 350
GVWEEWGSWS LCSRSCGRGS RSRMRTCVPP QHGGKACEGP ELQTKLCSMA
360 370 380 390 400
ACPVEGQWLE WGPWGPCSSS CANGTQQRSR KCSVAGPAWA TCAGALTDTR
410 420 430 440 450
ECSNLDCPAT DGKWGPWNAW SLCSKTCDTG WQRRFRMCQA SGTQGYPCEG
460 470 480 490 500
TGEEVKPCSE KRCPAFHEMC RDEYVMLMTW KRAAAGEIIY NKCPPNASGS
510 520 530 540 550
ASRRCLLSAQ GVAYWGLPSF ARCISHEYRY LYLSLREHLA KGQRMLAGEG
560 570 580 590 600
MSQVVRSLQE LLARRTYYSG DLLFSVDILR NVTDTFKRAT YVPSADDVQR
610 620 630 640 650
FFQVVSFMVD SENKDKWDDA QQVSPGSVHL LRVVEDFIHL VGDALKAFQS
660 670 680 690 700
SLIVTDNLVI SIQREPISAV SSDITFPMRG RRGMKDWVRH SEDRLFLPKE
710 720 730 740 750
VLSLSSPGKP ATPGAATAGS PGRGRGPGTV PPGPGHAHQR LLPADPEESS
760 770 780 790 800
SYFVIGAVLY RTLGLILPPP RPPLAVTSRV MTVTVRPPTQ PPAEPLITVE
810 820 830 840 850
LSYIINGTTD PHCASWDYSR ADTNSGDWNT ESCQTLETQA AHTRCQCQHL
860 870 880 890 900
STFAVLAQPP KDLTLELAGA PSVPLVIGCA VSCMALLTLL AIYAAFWRFI
910 920 930 940 950
KSERSIILLN FCLSILASNI LILVGQSRVL SKGVCTMTAA FLHFFFLSSF
960 970 980 990 1000
CWVLTEAWQS YLAVIGRMRT RLVRKRFLCL GWGLPALVVA VSVGFTRTKG
1010 1020 1030 1040 1050
YGTSSYCWLS LEGGLLYAFV GPAAVIVLVN MLIGIIVFNK LMARDGVSDK
1060 1070 1080 1090 1100
SKKQRAGASL WSSCVVLPLL ALTWMSAVLA MTDRRSVLFQ ALFAVFNSAQ
1110 1120 1130 1140 1150
GFVITAVHCF LRREVQDVVK CQMGVCRADE SEDSPDSCKN GQLQILSDFE
1160 1170 1180 1190 1200
KDVDLACQTV LFKEVNTCNP STITGTLSRL SLDEDEEPKS CLVGPEGGLS
1210 1220 1230 1240 1250
FSPLPGNILV PMAASPGLGE PPPPQETNPV YMCGEGGLRQ LDLTWIRQSE
1260 1270 1280 1290 1300
PGSEGDYMVL PRRTLSLQPG GGGTAGEEAP RARPEGTPRR AAKTVAHTEG
1310 1320 1330 1340 1350
YPSFLSVEHS GLGLGPAYGS LQNPYGMTFQ PPPPTPSARQ VPEPGERSRT
1360 1370 1380 1390 1400
MPRTVPGSTM KLGSLERKKL RYSDLDFEKV MHTRKRHSEL YHELNQKFHT
1410 1420 1430 1440 1450
FDRYRSQSSA KVRWMRGCNR LALLLSQEKP SPPGGRPGLS QHRRHQSWST
1460 1470 1480
FKSMTLGSLP PKPRERLALH RTAAWEPTEP PDGDFQTEV
Length:1,489
Mass (Da):162,633
Last modified:April 18, 2012 - v1
Checksum:iAEB78464AFD52F2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL626774 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000106018; ENSMUSP00000101639; ENSMUSG00000028782.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL626774 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000106018; ENSMUSP00000101639; ENSMUSG00000028782.

Organism-specific databases

MGIiMGI:2451244. Adgrb2.

Phylogenomic databases

GeneTreeiENSGT00820000126962.

Miscellaneous databases

ChiTaRSiBai2. mouse.
NextBioi35562293.
SOURCEiSearch...

Gene expression databases

BgeeiH7BX92.

Family and domain databases

InterProiIPR032471. GAIN_dom_N.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
IPR000884. TSP1_rpt.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF16489. GAIN. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 3 hits.
[Graphical view]
PRINTSiPR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 3 hits.
PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
    Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
    J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6J.
  5. Ensembl
    Submitted (JUN-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH7BX92_MOUSE
AccessioniPrimary (citable) accession number: H7BX92
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: January 20, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.