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H7BX74

- H7BX74_MOUSE

UniProt

H7BX74 - H7BX74_MOUSE

Protein
Submitted name:

Brain-specific angiogenesis inhibitor 2

Gene

Bai2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: InterPro

    GO - Biological processi

    1. negative regulation of angiogenesis Source: InterPro
    2. neuropeptide signaling pathway Source: InterPro
    3. peripheral nervous system development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Brain-specific angiogenesis inhibitor 2Imported
    Gene namesi
    Name:Bai2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:2451244. Bai2.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    BgeeiH7BX74.

    Family & Domainsi

    Sequence similaritiesi

    Contains GPS domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00690000101769.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view]
    PRINTSiPR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTiSM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 4 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 4 hits.
    PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H7BX74-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA     50
    SGCSWTLENP DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP 100
    GPEEATARAE SEVGRPEEEE EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ 150
    LCLSAEPSEA PRLLAPAALA FRFVEVLLIN NNNSSQFTCG VLCRWSEECG 200
    RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN ALVPGGPAPP 250
    AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTGD 300
    PAAEEWSPWS VCSLTCGQGL QVRTRSCVSS PYGTLCSGPL RETRPCNNSA 350
    TCPVHGVWEE WGSWSLCSRS CGRGSRSRMR TCVPPQHGGK ACEGPELQTK 400
    LCSMAACPVE GQWLEWGPWG PCSSSCANGT QQRSRKCSVA GPAWATCAGA 450
    LTDTRECSNL DCPATDGKWG PWNAWSLCSK TCDTGWQRRF RMCQASGTQG 500
    YPCEGTGEEV KPCSEKRCPA FHEMCRDEYV MLMTWKRAAA GEIIYNKCPP 550
    NASGSASRRC LLSAQGVAYW GLPSFARCIS HEYRYLYLSL REHLAKGQRM 600
    LAGEGMSQVV RSLQELLARR TYYSGDLLFS VDILRNVTDT FKRATYVPSA 650
    DDVQRFFQVV SFMVDSENKD KWDDAQQVSP GSVHLLRVVE DFIHLVGDAL 700
    KAFQSSLIVT DNLVISIQRE PISAVSSDIT FPMRGRRGMK DWVRHSEDRL 750
    FLPKEVLSLS SPGKPATPGA ATAGSPGRGR GPGTVPPGPG HAHQRLLPAD 800
    PEESSSYFVI GAVLYRTLGL ILPPPRPPLA VTSRVMTVTV RPPTQPPAEP 850
    LITVELSYII NGTTDPHCAS WDYSRADTNS GDWNTESCQT LETQAAHTRC 900
    QCQHLSTFAV LAQPPKDLTL ELAGAPSVPL VIGCAVSCMA LLTLLAIYAA 950
    FWRFIKSERS IILLNFCLSI LASNILILVG QSRVLSKGVC TMTAAFLHFF 1000
    FLSSFCWVLT EAWQSYLAVI GRMRTRLVRK RFLCLGWGLP ALVVAVSVGF 1050
    TRTKGYGTSS YCWLSLEGGL LYAFVGPAAV IVLVNMLIGI IVFNKLMARD 1100
    GVSDKSKKQR AGASLWSSCV VLPLLALTWM SAVLAMTDRR SVLFQALFAV 1150
    FNSAQGFVIT AVHCFLRREV QDVVKCQMGV CRADESEDSP DSCKNGQLQI 1200
    LSDFEKDVDL ACQTVLFKEV NTCNPSTITG TLSRLSLDED EEPKSCLVGP 1250
    EGGLSFSPLP GNILVPMAAS PGLGEPPPPQ ETNPVYMCGE GGLRQLDLTW 1300
    IRQSEPGSEG DYMVLPRRTL SLQPGGGGTA GEEAPRARPE GTPRRAAKTV 1350
    AHTEGYPSFL SVEHSGLGLG PAYGSLQNPY GMTFQPPPPT PSARQVPEPG 1400
    ERSRTMPRTV PGSTMKLGSL ERKKLRYSDL DFEKVMHTRK RHSELYHELN 1450
    QKFHTFDRYR SQSSAKVRWM RGCNRLALLL SQEKPSPPGG RPGLSQHRRH 1500
    QSWSTFKSMT LGSLPPKPRE RLALHRTAAW EPTEPPDGDF QTEV 1544
    Length:1,544
    Mass (Da):168,432
    Last modified:April 18, 2012 - v1
    Checksum:i4606AE8C2BC2F28E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000097868; ENSMUSP00000095480; ENSMUSG00000028782.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000097868 ; ENSMUSP00000095480 ; ENSMUSG00000028782 .

    Organism-specific databases

    MGIi MGI:2451244. Bai2.

    Phylogenomic databases

    GeneTreei ENSGT00690000101769.

    Miscellaneous databases

    ChiTaRSi BAI2. mouse.
    NextBioi 35562283.
    SOURCEi Search...

    Gene expression databases

    Bgeei H7BX74.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view ]
    PRINTSi PR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTi SM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 4 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 4 hits.
    PROSITEi PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
      J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiH7BX74_MOUSE
    AccessioniPrimary (citable) accession number: H7BX74
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3