Brain-specific angiogenesis inhibitor 2

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H7BX74 (H7BX74_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 10. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Brain-specific angiogenesis inhibitor 2 Ensembl ENSMUSP00000095480

Gene names

Name:

Bai2 Ensembl ENSMUSP00000095480 MGI 2451244

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000095480

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1544 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 GPS domain. SAAS SAAS000203
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000095480

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS000203 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000203
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	negative regulation of angiogenesis Inferred from electronic annotation. Source: InterPro neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro peripheral nervous system development Inferred from direct assay PubMed 12218411. Source: MGI
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

H7BX74 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 4606AE8C2BC2F28E
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FASTA

1,544

168,432

        10         20         30         40         50         60 
MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA SGCSWTLENP 

        70         80         90        100        110        120 
DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP GPEEATARAE SEVGRPEEEE 

       130        140        150        160        170        180 
EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ LCLSAEPSEA PRLLAPAALA FRFVEVLLIN 

       190        200        210        220        230        240 
NNNSSQFTCG VLCRWSEECG RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN 

       250        260        270        280        290        300 
ALVPGGPAPP AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTGD 

       310        320        330        340        350        360 
PAAEEWSPWS VCSLTCGQGL QVRTRSCVSS PYGTLCSGPL RETRPCNNSA TCPVHGVWEE 

       370        380        390        400        410        420 
WGSWSLCSRS CGRGSRSRMR TCVPPQHGGK ACEGPELQTK LCSMAACPVE GQWLEWGPWG 

       430        440        450        460        470        480 
PCSSSCANGT QQRSRKCSVA GPAWATCAGA LTDTRECSNL DCPATDGKWG PWNAWSLCSK 

       490        500        510        520        530        540 
TCDTGWQRRF RMCQASGTQG YPCEGTGEEV KPCSEKRCPA FHEMCRDEYV MLMTWKRAAA 

       550        560        570        580        590        600 
GEIIYNKCPP NASGSASRRC LLSAQGVAYW GLPSFARCIS HEYRYLYLSL REHLAKGQRM 

       610        620        630        640        650        660 
LAGEGMSQVV RSLQELLARR TYYSGDLLFS VDILRNVTDT FKRATYVPSA DDVQRFFQVV 

       670        680        690        700        710        720 
SFMVDSENKD KWDDAQQVSP GSVHLLRVVE DFIHLVGDAL KAFQSSLIVT DNLVISIQRE 

       730        740        750        760        770        780 
PISAVSSDIT FPMRGRRGMK DWVRHSEDRL FLPKEVLSLS SPGKPATPGA ATAGSPGRGR 

       790        800        810        820        830        840 
GPGTVPPGPG HAHQRLLPAD PEESSSYFVI GAVLYRTLGL ILPPPRPPLA VTSRVMTVTV 

       850        860        870        880        890        900 
RPPTQPPAEP LITVELSYII NGTTDPHCAS WDYSRADTNS GDWNTESCQT LETQAAHTRC 

       910        920        930        940        950        960 
QCQHLSTFAV LAQPPKDLTL ELAGAPSVPL VIGCAVSCMA LLTLLAIYAA FWRFIKSERS 

       970        980        990       1000       1010       1020 
IILLNFCLSI LASNILILVG QSRVLSKGVC TMTAAFLHFF FLSSFCWVLT EAWQSYLAVI 

      1030       1040       1050       1060       1070       1080 
GRMRTRLVRK RFLCLGWGLP ALVVAVSVGF TRTKGYGTSS YCWLSLEGGL LYAFVGPAAV 

      1090       1100       1110       1120       1130       1140 
IVLVNMLIGI IVFNKLMARD GVSDKSKKQR AGASLWSSCV VLPLLALTWM SAVLAMTDRR 

      1150       1160       1170       1180       1190       1200 
SVLFQALFAV FNSAQGFVIT AVHCFLRREV QDVVKCQMGV CRADESEDSP DSCKNGQLQI 

      1210       1220       1230       1240       1250       1260 
LSDFEKDVDL ACQTVLFKEV NTCNPSTITG TLSRLSLDED EEPKSCLVGP EGGLSFSPLP 

      1270       1280       1290       1300       1310       1320 
GNILVPMAAS PGLGEPPPPQ ETNPVYMCGE GGLRQLDLTW IRQSEPGSEG DYMVLPRRTL 

      1330       1340       1350       1360       1370       1380 
SLQPGGGGTA GEEAPRARPE GTPRRAAKTV AHTEGYPSFL SVEHSGLGLG PAYGSLQNPY 

      1390       1400       1410       1420       1430       1440 
GMTFQPPPPT PSARQVPEPG ERSRTMPRTV PGSTMKLGSL ERKKLRYSDL DFEKVMHTRK 

      1450       1460       1470       1480       1490       1500 
RHSELYHELN QKFHTFDRYR SQSSAKVRWM RGCNRLALLL SQEKPSPPGG RPGLSQHRRH 

      1510       1520       1530       1540 
QSWSTFKSMT LGSLPPKPRE RLALHRTAAW EPTEPPDGDF QTEV

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000095480.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000095480.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL626774 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000097868; ENSMUSP00000095480; ENSMUSG00000028782.
Organism-specific databases
MGI	MGI:2451244. Bai2.
Phylogenomic databases
GeneTree	ENSGT00690000101769.
Gene expression databases
ArrayExpress	H7BX74.
Bgee	H7BX74.
Family and domain databases
InterPro	IPR022624. DUF3497. IPR017981. GPCR_2-like. IPR008077. GPCR_2_brain-spec_angio_inhib. IPR001879. GPCR_2_extracellular_dom. IPR000832. GPCR_2_secretin-like. IPR000203. GPS_dom. IPR000884. Thrombospondin_1_rpt. [Graphical view]
Pfam	PF00002. 7tm_2. 1 hit. PF12003. DUF3497. 1 hit. PF01825. GPS. 1 hit. PF00090. TSP_1. 4 hits. [Graphical view]
PRINTS	PR01694. BAIPRECURSOR. PR00249. GPCRSECRETIN.
SMART	SM00303. GPS. 1 hit. SM00008. HormR. 1 hit. SM00209. TSP1. 4 hits. [Graphical view]
SUPFAM	SSF82895. TSP1. 4 hits.
PROSITE	PS50227. G_PROTEIN_RECEP_F2_3. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. PS50221. GPS. 1 hit. PS50092. TSP1. 4 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	BAI2. mouse.
NextBio	35562283.
SOURCE	Search...

Entry information

Entry name

H7BX74_MOUSE

Accession

Primary (citable) accession number: H7BX74

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2012
Last sequence update:	April 18, 2012
Last modified:	April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information