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Protein
Submitted name:

Thioredoxin domain-containing protein 2

Gene

Txndc2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. protein disulfide isomerase activity Source: MGI
  2. protein disulfide oxidoreductase activity Source: InterPro
  3. thioredoxin-disulfide reductase activity Source: MGI

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
  2. glycerol ether metabolic process Source: InterPro
  3. oxidation-reduction process Source: MGI
  4. protein folding Source: GOC
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Thioredoxin domain-containing protein 2Imported
Gene namesi
Name:Txndc2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:2389312. Txndc2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. motile cilium Source: MGI
  3. nucleolus Source: MGI
  4. nucleoplasm Source: MGI
  5. nucleus Source: MGI
  6. outer dense fiber Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiH7BX21.
ExpressionAtlasiH7BX21. baseline.

Structurei

3D structure databases

ProteinModelPortaliH7BX21.
SMRiH7BX21. Positions 446-549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063008.
OMAiKTIPPKQ.
OrthoDBiEOG7H4DX9.
TreeFamiTF106377.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
[Graphical view]
PANTHERiPTHR10438. PTHR10438. 1 hit.
PfamiPF00085. Thioredoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H7BX21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLAIEEMFK KDKQKNKDKG LDMNSVQAGA PEESDMTLNN GGKANERGSN
60 70 80 90 100
ENPLQALSKN EAFLVPEFLD TAQSKEKAIA SKVSNTLHMS TEESEFPQQV
110 120 130 140 150
SSTPMFSENT VHPRHEVSPK PSSKNTQLKQ ENISKSSGYS KQTNYSNTPK
160 170 180 190 200
SLAKTTHPKQ GSTLKPATNS THYREDDIPK SSEDIIQPKK GDRPKSSEDI
210 220 230 240 250
IQSKKEDRPK SSEDIIQSKK EDRPKSSEDI IQSKKEDRPK SSEDIIQSKK
260 270 280 290 300
EDRPKSSEDI IQPKKEDRPK SSEDSVPSKK GDRPKSSEDS VQPKKEDRPK
310 320 330 340 350
SSEDSVQSKE GEVHKPLKDS IQSKETKVPK SPQDSIQSKE DKTHRPLKDS
360 370 380 390 400
VQSKESEEPK SSHESIQSKE DKIHKPLKDS IPSKEGDIPK SPEDTIQSQE
410 420 430 440 450
EITASEEDTI QSQEGNTIKS SEEDVQLSES KLLGLGAEIE TLEEGLVRVI
460 470 480 490 500
KDKEEFEEVL KDAGEKLVAV DFSAAWCGPC RMMKPLFHSL SLKHEDVIFL
510 520 530 540 550
EVDTEDCEQL VQDCEIFHLP TFQFYKNEEK VGEFSGALVG KLERSISELK
Length:550
Mass (Da):61,690
Last modified:April 18, 2012 - v1
Checksum:iF17AC964826F2357
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166058 Genomic DNA. No translation available.
RefSeqiNP_001139474.1. NM_001146002.1.
UniGeneiMm.255732.

Genome annotation databases

EnsembliENSMUST00000050236; ENSMUSP00000054909; ENSMUSG00000050612.
GeneIDi213272.
KEGGimmu:213272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166058 Genomic DNA. No translation available.
RefSeqiNP_001139474.1. NM_001146002.1.
UniGeneiMm.255732.

3D structure databases

ProteinModelPortaliH7BX21.
SMRiH7BX21. Positions 446-549.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000050236; ENSMUSP00000054909; ENSMUSG00000050612.
GeneIDi213272.
KEGGimmu:213272.

Organism-specific databases

CTDi84203.
MGIiMGI:2389312. Txndc2.

Phylogenomic databases

GeneTreeiENSGT00530000063008.
OMAiKTIPPKQ.
OrthoDBiEOG7H4DX9.
TreeFamiTF106377.

Miscellaneous databases

NextBioi373905.
SOURCEiSearch...

Gene expression databases

BgeeiH7BX21.
ExpressionAtlasiH7BX21. baseline.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
[Graphical view]
PANTHERiPTHR10438. PTHR10438. 1 hit.
PfamiPF00085. Thioredoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH7BX21_MOUSE
AccessioniPrimary (citable) accession number: H7BX21
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: March 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.