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H7BX21

- H7BX21_MOUSE

UniProt

H7BX21 - H7BX21_MOUSE

Protein
Submitted name:

Thioredoxin domain-containing protein 2

Gene

Txndc2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein disulfide isomerase activity Source: MGI
    2. protein disulfide oxidoreductase activity Source: InterPro

    GO - Biological processi

    1. cell redox homeostasis Source: InterPro
    2. glycerol ether metabolic process Source: InterPro
    3. protein folding Source: GOC

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Thioredoxin domain-containing protein 2Imported
    Gene namesi
    Name:Txndc2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:2389312. Txndc2.

    Subcellular locationi

    GO - Cellular componenti

    1. motile cilium Source: MGI
    2. nucleolus Source: Ensembl
    3. outer dense fiber Source: Ensembl

    Expressioni

    Gene expression databases

    BgeeiH7BX21.

    Structurei

    3D structure databases

    ProteinModelPortaliH7BX21.
    SMRiH7BX21. Positions 446-549.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063008.
    OMAiKTIPPKQ.
    OrthoDBiEOG7H4DX9.
    TreeFamiTF106377.

    Family and domain databases

    Gene3Di3.40.30.10. 1 hit.
    InterProiIPR005746. Thioredoxin.
    IPR012336. Thioredoxin-like_fold.
    IPR013766. Thioredoxin_domain.
    [Graphical view]
    PANTHERiPTHR10438. PTHR10438. 1 hit.
    PfamiPF00085. Thioredoxin. 1 hit.
    [Graphical view]
    SUPFAMiSSF52833. SSF52833. 1 hit.
    PROSITEiPS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H7BX21-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLAIEEMFK KDKQKNKDKG LDMNSVQAGA PEESDMTLNN GGKANERGSN    50
    ENPLQALSKN EAFLVPEFLD TAQSKEKAIA SKVSNTLHMS TEESEFPQQV 100
    SSTPMFSENT VHPRHEVSPK PSSKNTQLKQ ENISKSSGYS KQTNYSNTPK 150
    SLAKTTHPKQ GSTLKPATNS THYREDDIPK SSEDIIQPKK GDRPKSSEDI 200
    IQSKKEDRPK SSEDIIQSKK EDRPKSSEDI IQSKKEDRPK SSEDIIQSKK 250
    EDRPKSSEDI IQPKKEDRPK SSEDSVPSKK GDRPKSSEDS VQPKKEDRPK 300
    SSEDSVQSKE GEVHKPLKDS IQSKETKVPK SPQDSIQSKE DKTHRPLKDS 350
    VQSKESEEPK SSHESIQSKE DKIHKPLKDS IPSKEGDIPK SPEDTIQSQE 400
    EITASEEDTI QSQEGNTIKS SEEDVQLSES KLLGLGAEIE TLEEGLVRVI 450
    KDKEEFEEVL KDAGEKLVAV DFSAAWCGPC RMMKPLFHSL SLKHEDVIFL 500
    EVDTEDCEQL VQDCEIFHLP TFQFYKNEEK VGEFSGALVG KLERSISELK 550
    Length:550
    Mass (Da):61,690
    Last modified:April 18, 2012 - v1
    Checksum:iF17AC964826F2357
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC166058 Genomic DNA. No translation available.
    RefSeqiNP_001139474.1. NM_001146002.1.
    UniGeneiMm.255732.

    Genome annotation databases

    EnsembliENSMUST00000050236; ENSMUSP00000054909; ENSMUSG00000050612.
    GeneIDi213272.
    KEGGimmu:213272.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC166058 Genomic DNA. No translation available.
    RefSeqi NP_001139474.1. NM_001146002.1.
    UniGenei Mm.255732.

    3D structure databases

    ProteinModelPortali H7BX21.
    SMRi H7BX21. Positions 446-549.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000050236 ; ENSMUSP00000054909 ; ENSMUSG00000050612 .
    GeneIDi 213272.
    KEGGi mmu:213272.

    Organism-specific databases

    CTDi 84203.
    MGIi MGI:2389312. Txndc2.

    Phylogenomic databases

    GeneTreei ENSGT00530000063008.
    OMAi KTIPPKQ.
    OrthoDBi EOG7H4DX9.
    TreeFami TF106377.

    Miscellaneous databases

    NextBioi 373905.
    SOURCEi Search...

    Gene expression databases

    Bgeei H7BX21.

    Family and domain databases

    Gene3Di 3.40.30.10. 1 hit.
    InterProi IPR005746. Thioredoxin.
    IPR012336. Thioredoxin-like_fold.
    IPR013766. Thioredoxin_domain.
    [Graphical view ]
    PANTHERi PTHR10438. PTHR10438. 1 hit.
    Pfami PF00085. Thioredoxin. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52833. SSF52833. 1 hit.
    PROSITEi PS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiH7BX21_MOUSE
    AccessioniPrimary (citable) accession number: H7BX21
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3