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H7BWZ2

- H7BWZ2_MOUSE

UniProt

H7BWZ2 - H7BWZ2_MOUSE

Protein
Submitted name:

Brain-specific angiogenesis inhibitor 2

Gene

Bai2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: InterPro

    GO - Biological processi

    1. negative regulation of angiogenesis Source: InterPro
    2. neuropeptide signaling pathway Source: InterPro
    3. peripheral nervous system development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Brain-specific angiogenesis inhibitor 2Imported
    Gene namesi
    Name:Bai2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:2451244. Bai2.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    BgeeiH7BWZ2.

    Family & Domainsi

    Sequence similaritiesi

    Contains GPS domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00690000101769.
    OMAiEQVCAHF.

    Family and domain databases

    InterProiIPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view]
    PRINTSiPR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTiSM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 4 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 4 hits.
    PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H7BWZ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA     50
    SGCSWTLENP DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP 100
    GPEEATARAE SEVGRPEEEE EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ 150
    LCLSAEPSEA PRLLAPAALA FRFVEVLLIN NNNSSQFTCG VLCRWSEECG 200
    RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN ALVPGGPAPP 250
    AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTGD 300
    PAAEEWSPWS VCSLTCGQGL QVRTRSCVSS PYGTLCSGPL RETRPCNNSA 350
    TCPVHGVWEE WGSWSLCSRS CGRGSRSRMR TCVPPQHGGK ACEGPELQTK 400
    LCSMAACPVE GQWLEWGPWG PCSSSCANGT QQRSRKCSVA GPAWATCAGA 450
    LTDTRECSNL DCPATDGKWG PWNAWSLCSK TCDTGWQRRF RMCQASGTQG 500
    YPCEGTGEEV KPCSEKRCPA FHEMCRDEYV MLMTWKRAAA GEIIYNKCPP 550
    NASGSASRRC LLSAQGVAYW GLPSFARCIS HEYRYLYLSL REHLAKGQRM 600
    LAGEGMSQVV RSLQELLARR TYYSGDLLFS VDILRNVTDT FKRATYVPSA 650
    DDVQRFFQVV SFMVDSENKD KWDDAQQVSP GSVHLLRVVE DFIHLVGDAL 700
    KAFQSSLIVT DNLVISIQRE PISAVSSDIT FPMRGRRGMK DWVRHSEDRL 750
    FLPKEVLSLS SPGKPATPGA ATAGSPGRGR GPGTVPPGPG HAHQRLLPAD 800
    PEESSSYFVI GAVLYRTLGL ILPPPRPPLA VTSRVMTVTV RPPTQPPAEP 850
    LITVELSYII NGTTDPHCAS WDYSRADTNS GDWNTESCQT LETQAAHTRC 900
    QCQHLSTFAV LAQPPKDLTL ELAGAPSVPL VIGCAVSCMA LLTLLAIYAA 950
    FWRFIKSERS IILLNFCLSI LASNILILVG QSRVLSKGVC TMTAAFLHFF 1000
    FLSSFCWVLT EAWQSYLAVI GRMRTRLVRK RFLCLGWGLP ALVVAVSVGF 1050
    TRTKGYGTSS YCWLSLEGGL LYAFVGPAAV IVLVNMLIGI IVFNKLMARD 1100
    GVSDKSKKQR AGSERCPWAS LLLPCSACGA VPSPLLSSAS ARNAMASLWS 1150
    SCVVLPLLAL TWMSAVLAMT DRRSVLFQAL FAVFNSAQGF VITAVHCFLR 1200
    REVQDVVKCQ MGVCRADESE DSPDSCKNGQ LQILSDFEKD VDLACQTVLF 1250
    KEVNTCNPST ITGTLSRLSL DEDEEPKSCL VGPEGGLSFS PLPGNILVPM 1300
    AASPGLGEPP PPQETNPVYM CGEGGLRQLD LTWIRQSEPG SEGDYMVLPR 1350
    RTLSLQPGGG GTAGEEAPRA RPEGTPRRAA KTVAHTEGYP SFLSVEHSGL 1400
    GLGPAYGSLQ NPYGMTFQPP PPTPSARQVP EPGERSRTMP RTVPGSTMKL 1450
    GSLERKKLRY SDLDFEKVMH TRKRHSELYH ELNQKFHTFD RYRSQSSAKV 1500
    RWMRGCNRLA LLLSQEKPSP PGGRPGLSQH RRHQSWSTFK SMTLGSLPPK 1550
    PRERLALHRT AAWEPTEPPD GDFQTEV 1577
    Length:1,577
    Mass (Da):171,761
    Last modified:April 18, 2012 - v1
    Checksum:iB387101E434C364F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000030571; ENSMUSP00000030571; ENSMUSG00000028782.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000030571 ; ENSMUSP00000030571 ; ENSMUSG00000028782 .

    Organism-specific databases

    MGIi MGI:2451244. Bai2.

    Phylogenomic databases

    GeneTreei ENSGT00690000101769.
    OMAi EQVCAHF.

    Miscellaneous databases

    ChiTaRSi BAI2. mouse.
    NextBioi 35562258.
    SOURCEi Search...

    Gene expression databases

    Bgeei H7BWZ2.

    Family and domain databases

    InterProi IPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view ]
    PRINTSi PR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTi SM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 4 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 4 hits.
    PROSITEi PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
      J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiH7BWZ2_MOUSE
    AccessioniPrimary (citable) accession number: H7BWZ2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3