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Protein
Submitted name:

Disks large homolog 1

Gene

Dlg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Disks large homolog 1Imported
Gene namesi
Name:Dlg1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:107231. Dlg1.

PTM / Processingi

Proteomic databases

EPDiH7BWY4.
MaxQBiH7BWY4.

Expressioni

Gene expression databases

BgeeiH7BWY4.
ExpressionAtlasiH7BWY4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH7BWY4.
SMRiH7BWY4. Positions 2-65, 188-872.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 6461L27InterPro annotationAdd
BLAST
Domaini191 – 27888PDZ (DHR)InterPro annotationAdd
BLAST
Domaini286 – 37388PDZ (DHR)InterPro annotationAdd
BLAST
Domaini433 – 51482PDZ (DHR)InterPro annotationAdd
BLAST
Domaini548 – 61871SH3InterPro annotationAdd
BLAST
Domaini682 – 857176Guanylate kinase-likeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains 3 PDZ (DHR) domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118866.

Family and domain databases

Gene3Di2.30.42.10. 3 hits.
3.40.50.300. 2 hits.
InterProiIPR016313. DLG1.
IPR019590. DLG1_PEST_dom.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR015143. L27_1.
IPR004172. L27_dom.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
PF09058. L27_1. 1 hit.
PF10608. MAGUK_N_PEST. 2 hits.
PF00595. PDZ. 3 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PIRSFiPIRSF001741. MAGUK_DLGH. 1 hit.
SMARTiSM00072. GuKc. 1 hit.
SM00569. L27. 1 hit.
SM01277. MAGUK_N_PEST. 1 hit.
SM00228. PDZ. 3 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF101288. SSF101288. 1 hit.
SSF50044. SSF50044. 2 hits.
SSF50156. SSF50156. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS51022. L27. 1 hit.
PS50106. PDZ. 3 hits.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H7BWY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVRKQDTQR ALHLLEEYRS KLSQTEDRQL RSSIERVINI FQSNLFQALI
60 70 80 90 100
DIQEFYEVTL LDNPKCVDHS KQCEPVQPVT TWEIASLPST AVTSETLPGS
110 120 130 140 150
LSPPVEKYRY QDEEVLPPEH ISPQVTNEVL GPELVHVSEK NLSEIENVHG
160 170 180 190 200
FVSHSHISPI KANPPPVLVN TDSLETPTYV NGTDADYEYE EITLERGNSG
210 220 230 240 250
LGFSIAGGTD NPHIGDDSSI FITKIITGGA AAQDGRLRVN DCILRVNEAD
260 270 280 290 300
VRDVTHSKAV EALKEAGSIV RLYVKRRKPA SEKIMEIKLI KGPKGLGFSI
310 320 330 340 350
AGGVGNQHIP GDNSIYVTKI IEGGAAHKDG KLQIGDKLLA VNSVCLEEVT
360 370 380 390 400
HEEAVTALKN TSDFVYLKVA KPTSMYINDG YAPPDITNSS SQSVDNHVSP
410 420 430 440 450
SSCLGQTPTS PARYSPISKA VLGDDEITRE PRKVVLHRGS TGLGFNIVGG
460 470 480 490 500
EDGEGIFISF ILAGGPADLS GELRKGDRII SVNSVDLRAA SHEQAAAALK
510 520 530 540 550
NAGQAVTIVA QYRPEEYSRF EAKIHDLREQ MMNSSVSSGS GSLRTSQKRS
560 570 580 590 600
LYVRALFDYD KTKDSGLPSQ GLNFRFGDIL HVINASDDEW WQARQVTPDG
610 620 630 640 650
ESDEVGVIPS KRRVEKKERA RLKTVKFNSK TRGDKGEIPD DMGSKGLKHV
660 670 680 690 700
TSNASDSESS YRGQEEYVLS YEPVNQQEVN YTRPVIILGP MKDRVNDDLI
710 720 730 740 750
SEFPDKFGSC VPHTTRPKRD YEVDGRDYHF VTSREQMEKD IQEHKFIEAG
760 770 780 790 800
QYNNHLYGTS VQSVRAVAEK GKHCILDVSG NAIKRLQIAQ LYPISIFIKP
810 820 830 840 850
KSMENIMEMN KRLTEEQARK TFERAMKLEQ EFTEHFTAIV QGDTLEDIYN
860 870
QVKQIIEEQS GPYIWVPAKE KL
Length:872
Mass (Da):96,892
Last modified:April 18, 2012 - v1
Checksum:i23B2B021CD96BC0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126055 Genomic DNA. No translation available.
AC129214 Genomic DNA. No translation available.
RefSeqiNP_001239363.1. NM_001252434.1.
UniGeneiMm.382.

Genome annotation databases

EnsembliENSMUST00000023454; ENSMUSP00000023454; ENSMUSG00000022770.
GeneIDi13383.
UCSCiuc007yxr.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126055 Genomic DNA. No translation available.
AC129214 Genomic DNA. No translation available.
RefSeqiNP_001239363.1. NM_001252434.1.
UniGeneiMm.382.

3D structure databases

ProteinModelPortaliH7BWY4.
SMRiH7BWY4. Positions 2-65, 188-872.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH7BWY4.
MaxQBiH7BWY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000023454; ENSMUSP00000023454; ENSMUSG00000022770.
GeneIDi13383.
UCSCiuc007yxr.2. mouse.

Organism-specific databases

CTDi1739.
MGIiMGI:107231. Dlg1.

Phylogenomic databases

GeneTreeiENSGT00760000118866.

Miscellaneous databases

ChiTaRSiDlg1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiH7BWY4.
ExpressionAtlasiH7BWY4. baseline and differential.

Family and domain databases

Gene3Di2.30.42.10. 3 hits.
3.40.50.300. 2 hits.
InterProiIPR016313. DLG1.
IPR019590. DLG1_PEST_dom.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR015143. L27_1.
IPR004172. L27_dom.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
PF09058. L27_1. 1 hit.
PF10608. MAGUK_N_PEST. 2 hits.
PF00595. PDZ. 3 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PIRSFiPIRSF001741. MAGUK_DLGH. 1 hit.
SMARTiSM00072. GuKc. 1 hit.
SM00569. L27. 1 hit.
SM01277. MAGUK_N_PEST. 1 hit.
SM00228. PDZ. 3 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF101288. SSF101288. 1 hit.
SSF50044. SSF50044. 2 hits.
SSF50156. SSF50156. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS51022. L27. 1 hit.
PS50106. PDZ. 3 hits.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
    Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
    J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH7BWY4_MOUSE
AccessioniPrimary (citable) accession number: H7BWY4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: June 8, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.