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Protein
Submitted name:

Interleukin 2 receptor alpha

Gene
N/A
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 2 receptor alphaImported
Submitted name:
Interleukin-2 receptor subunit alpha precursorImported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei239 – 261HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501430518022 – 272Sequence analysisAdd BLAST251

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 67PROSITE-ProRule annotation
Disulfide bondi125 ↔ 168PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 84SushiInterPro annotationAdd BLAST63
Domaini123 – 186SushiInterPro annotationAdd BLAST64

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000018872
KOiK05068

Family and domain databases

CDDicd00033 CCP, 1 hit
InterProiView protein in InterPro
IPR015486 IL-2_rcpt_alpha
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PANTHERiPTHR10573 PTHR10573, 1 hit
PfamiView protein in Pfam
PF00084 Sushi, 1 hit
SMARTiView protein in SMART
SM00032 CCP, 2 hits
SUPFAMiSSF57535 SSF57535, 2 hits
PROSITEiView protein in PROSITE
PS50923 SUSHI, 2 hits

Sequencei

Sequence statusi: Complete.

H6WS54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPYLLMWGL LTFITVPGCQ AELCDDDPPK ITHATFKAVA YKEGTMLNCE
60 70 80 90 100
CKRGFRRIKS GSPYMLCTGN SSHSSWDNQC QCTSSAARNT TKQVTPQPEE
110 120 130 140 150
QKERKTTEMQ SQMQLADQVS LPGHCREPPP WENEATERIY HFVVGQTVYY
160 170 180 190 200
QCVQGYRALH RGPAESVCKM THGKTRWTQP QLICTGETEP SQFPGEEEPQ
210 220 230 240 250
ASPDGLPESE TSRLVTTTDF RIQTEVAATM ETFIFTTEYQ VAVAGCVFLL
260 270
ISVLLLSGLT WQRRQRKNRR TI
Length:272
Mass (Da):30,787
Last modified:April 18, 2012 - v1
Checksum:i94F7A20A1B92DB99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01069900 Genomic DNA No translation available.
AQIA01069901 Genomic DNA No translation available.
AQIA01069902 Genomic DNA No translation available.
JQ288991 mRNA Translation: AEY84627.1
RefSeqiNP_001270633.1, NM_001283704.1

Genome annotation databases

EnsembliENSMFAT00000067997; ENSMFAP00000017455; ENSMFAG00000031840
GeneIDi102123605
KEGGimcf:102123605

Similar proteinsi

Entry informationi

Entry nameiH6WS54_MACFA
AccessioniPrimary (citable) accession number: H6WS54
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 25, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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