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Protein

Alpha-synuclein

Gene

SNCA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-synucleinUniRule annotation
Gene namesi
Name:SNCAImported
ORF Names:hCG_1777783Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSG00000145335.

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF5. PTHR13820:SF5. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Complete.

H6UYS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV VAEKTKEQVT
60 70 80 90 100
NVGGAVVTGV TAVAQKTVEG AGSIAAATGF VKKDQLGKNE EGAPQEGILE
110 120
DMPVDPDNEA YEMPSEEGYQ DYEPEA
Length:126
Mass (Da):13,109
Last modified:April 18, 2012 - v1
Checksum:i0F87D9A60E831E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN709859 mRNA. Translation: AFA25669.1.
JN709862 mRNA. Translation: AFA25672.1.
JN709865 mRNA. Translation: AFA25675.1.
JN709868 mRNA. Translation: AFA25678.1.
CH471057 Genomic DNA. Translation: EAX06035.1.
UniGeneiHs.21374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN709859 mRNA. Translation: AFA25669.1.
JN709862 mRNA. Translation: AFA25672.1.
JN709865 mRNA. Translation: AFA25675.1.
JN709868 mRNA. Translation: AFA25678.1.
CH471057 Genomic DNA. Translation: EAX06035.1.
UniGeneiHs.21374.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiSNCA. human.

Gene expression databases

BgeeiENSG00000145335.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF5. PTHR13820:SF5. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.
ProtoNetiSearch...

Entry informationi

Entry nameiH6UYS0_HUMAN
AccessioniPrimary (citable) accession number: H6UYS0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 30, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.