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H6SPP4

- H6SPP4_RHOPH

UniProt

H6SPP4 - H6SPP4_RHOPH

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Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL2

Organism
Rhodospirillum photometricum DSM 122
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei115 – 1151Substrate; in homodimeric partnerUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Active sitei167 – 1671Proton acceptorUniRule annotation
Binding sitei169 – 1691SubstrateUniRule annotation
Metal bindingi193 – 1931Magnesium; via carbamate groupUniRule annotation
Metal bindingi195 – 1951MagnesiumUniRule annotation
Metal bindingi196 – 1961MagnesiumUniRule annotation
Active sitei286 – 2861Proton acceptorUniRule annotation
Binding sitei287 – 2871SubstrateUniRule annotation
Binding sitei319 – 3191SubstrateUniRule annotation
Sitei326 – 3261Transition state stabilizerUniRule annotation
Binding sitei371 – 3711SubstrateUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRPHO1150469:GLJ6-619-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunitUniRule annotation
Gene namesi
Name:cbbL2Imported
Synonyms:cbbLUniRule annotation
ORF Names:RSPPHO_00538Imported
OrganismiRhodospirillum photometricum DSM 122Imported
Taxonomic identifieri1150469 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei193 – 1931N6-carboxylysineUniRule annotation

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

Phylogenomic databases

KOiK01601.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01338. RuBisCO_L_type1.
InterProiIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H6SPP4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKTYQAGVK EYRETYWDPN YTPKDSDILA CFKVVPQPGV PREEAAAAVC
60 70 80 90 100
AESSTATWTT VWTDLLTDLD YYKGRAYAIE DVPGHDEAFY AFIAYPMGLF
110 120 130 140 150
EEGSIVNVFT SLVGNVFGFK AVRSLRLEDV RFPLWFVTTC DGPPHGIQVE
160 170 180 190 200
RDLLDKYGRP LLGCTIKPKL GLSAKNYGRA VYECLRGGLD FTKDDENVNS
210 220 230 240 250
QPFMRWRDRF LFCQEAIEKA EAETGERKGH YLNVTAPTME DIYQRAAFAK
260 270 280 290 300
EIGTPIIMSD YLTIGWAAHA SLSRWCRNNG MLLHVHRAMH AVIDRNPMHG
310 320 330 340 350
INFRVLAKLL RLLGGDHLHS GTVVGKLEGD RDATLGWIDL MRERHVKEDR
360 370 380 390 400
SRGIFFDQDW GHMPSVMPVA SGGIHVWHMP ALLAIFGDDA VFQFGGGTLG
410 420 430 440 450
HPWGNAAGAA ANRVALEACV QARNEGRSLE SEGKAILTAA ARHSPELKMA
460 470
METWKEVKFE FETVDTLDVS HK
Length:472
Mass (Da):52,779
Last modified:April 18, 2012 - v1
Checksum:i9DBA64443B15D972
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE663493 Genomic DNA. Translation: CCG07164.1.
RefSeqiWP_014413804.1. NC_017059.1.
YP_005416134.1. NC_017059.1.

Genome annotation databases

EnsemblBacteriaiCCG07164; CCG07164; RSPPHO_00538.
GeneIDi12211237.
KEGGirpm:RSPPHO_00538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE663493 Genomic DNA. Translation: CCG07164.1 .
RefSeqi WP_014413804.1. NC_017059.1.
YP_005416134.1. NC_017059.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCG07164 ; CCG07164 ; RSPPHO_00538 .
GeneIDi 12211237.
KEGGi rpm:RSPPHO_00538.

Phylogenomic databases

KOi K01601.

Enzyme and pathway databases

BioCyci RPHO1150469:GLJ6-619-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01338. RuBisCO_L_type1.
InterProi IPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Shotgun genome sequence of Phaeospirillum photometricum DSM 122."
    Duquesne K., Sturgis J.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 122Imported.

Entry informationi

Entry nameiH6SPP4_RHOPH
AccessioniPrimary (citable) accession number: H6SPP4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

External Data

Dasty 3