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H6SNF2 (H6SNF2_RHOPH) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL CCG09283.1
ORF Names:RSPPHO_02657 EMBL CCG09283.1
OrganismRhodospirillum photometricum DSM 122 EMBL CCG09283.1
Taxonomic identifier1150469 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain106 – 298193ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding133 – 18553ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2531Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2671Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
H6SNF2 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 8AE6ED2111A9BB72

FASTA30432,130
        10         20         30         40         50         60 
MSRARRVTVL MGGCSAEREV SLNSGQAVGA ALARAGFAVD LLDVSRDVGA LVAALTARTP 

        70         80         90        100        110        120 
DVVFNALHGR FGEDGAIQGL LDLMGLPYTH SGRLASALAM DKPSAKLVFE HVGIPVAPHV 

       130        140        150        160        170        180 
IATPAEVLAE TVMPRPYVVK PLNEGSSVGV TIVTEGTNAL PFTATDWPFG KRVMVERFIP 

       190        200        210        220        230        240 
GRELTVAVMG ERALGVTEIT TSRGFYDYDA KYILGGSRHI VPAPVAPEVA TEAMRLAVLA 

       250        260        270        280        290        300 
HQALGCRGVS RADLRFDGES LFMLEVNTQP GMTGTSLVPE QALAVGLSFE ALVSWMVENA 


QCDT 

« Hide

References

[1]"Shotgun genome sequence of Phaeospirillum photometricum DSM 122."
Duquesne K., Sturgis J.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 122 EMBL CCG09283.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE663493 Genomic DNA. Translation: CCG09283.1.
RefSeqYP_005418253.1. NC_017059.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCG09283; CCG09283; RSPPHO_02657.
GeneID12212103.
KEGGrpm:RSPPHO_02657.

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycRPHO1150469:GLJ6-2788-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH6SNF2_RHOPH
AccessionPrimary (citable) accession number: H6SNF2
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: February 19, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)