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Protein

Cytochrome c oxidase subunit 6A, mitochondrial

Gene

COX6A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 6A, mitochondrialUniRule annotation
Alternative name(s):
Cytochrome c oxidase polypeptide VIaUniRule annotation
Gene namesi
Name:COX6A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000111775.2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 59HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiH6SG15.
PRIDEiH6SG15.

Expressioni

Gene expression databases

BgeeiENSG00000111775.
ExpressionAtlasiH6SG15. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH6SG15.
SMRiH6SG15.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 6A family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3469. Eukaryota.
ENOG411253X. LUCA.
KOiK02266.
OMAiHEEHERP.
OrthoDBiEOG091G0C5F.
PhylomeDBiH6SG15.

Family and domain databases

CDDicd00925. Cyt_c_Oxidase_VIa. 1 hit.
Gene3Di4.10.95.10. 1 hit.
InterProiView protein in InterPro
IPR001349. Cyt_c_oxidase_su6a.
IPR018507. Cyt_c_oxidase_su6a_CS.
IPR036418. Cyt_c_oxidase_su6a_sf.
PANTHERiPTHR11504. PTHR11504. 1 hit.
PfamiView protein in Pfam
PF02046. COX6A. 1 hit.
PIRSFiPIRSF000277. COX6A1. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006036. Cyt_c_oxidase_su6a. 1 hit.
SUPFAMiSSF81411. SSF81411. 1 hit.
PROSITEiView protein in PROSITE
PS01329. COX6A. 1 hit.

Sequencei

Sequence statusi: Complete.

H6SG15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVVGVSSVS RLLGRSRPQL GRPMSSGAHG EEGSARMWKT LTFFVALPGV
60 70 80 90 100
AVSMLNVYLK SHHGEHERPE FIAYPHLRIR TKPFPWGDGN HTLFHNPHVN

PLPTGYEDE
Length:109
Mass (Da):12,155
Last modified:April 18, 2012 - v1
Checksum:i0040F47CECE767B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE647860 mRNA. Translation: CCF23108.1.
RefSeqiNP_004364.2. NM_004373.3.
UniGeneiHs.369624.

Genome annotation databases

GeneIDi1337.
KEGGihsa:1337.

Similar proteinsi

Entry informationi

Entry nameiH6SG15_HUMAN
AccessioniPrimary (citable) accession number: H6SG15
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: October 25, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.