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H6SG15

- H6SG15_HUMAN

UniProt

H6SG15 - H6SG15_HUMAN

Protein

Cytochrome c oxidase subunit 6A, mitochondrial

Gene

COX6A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 6A, mitochondrialUniRule annotation
    Alternative name(s):
    Cytochrome c oxidase polypeptide VIaUniRule annotation
    Gene namesi
    Name:COX6A1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    Mitochondrion inner membrane UniRule annotation

    GO - Cellular componenti

    1. mitochondrial respiratory chain complex IV Source: InterPro

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiH6SG15.

    Expressioni

    Gene expression databases

    BgeeiH6SG15.

    Structurei

    3D structure databases

    ProteinModelPortaliH6SG15.
    SMRiH6SG15. Positions 25-107.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c oxidase subunit 6A family.UniRule annotation

    Phylogenomic databases

    KOiK02266.
    OMAiREKRFPW.
    PhylomeDBiH6SG15.

    Family and domain databases

    Gene3Di4.10.95.10. 1 hit.
    InterProiIPR001349. Cyt_c_oxidase_su6a.
    IPR018507. Cyt_c_oxidase_su6a_CS.
    [Graphical view]
    PANTHERiPTHR11504. PTHR11504. 1 hit.
    PfamiPF02046. COX6A. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000277. COX6A1. 1 hit.
    ProDomiPD006036. Cyt_c_oxidase_su6a. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF81411. SSF81411. 1 hit.
    PROSITEiPS01329. COX6A. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H6SG15-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVVGVSSVS RLLGRSRPQL GRPMSSGAHG EEGSARMWKT LTFFVALPGV    50
    AVSMLNVYLK SHHGEHERPE FIAYPHLRIR TKPFPWGDGN HTLFHNPHVN 100
    PLPTGYEDE 109
    Length:109
    Mass (Da):12,155
    Last modified:April 18, 2012 - v1
    Checksum:i0040F47CECE767B1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE647860 mRNA. Translation: CCF23108.1.
    RefSeqiNP_004364.2. NM_004373.3.
    UniGeneiHs.369624.

    Genome annotation databases

    GeneIDi1337.
    KEGGihsa:1337.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE647860 mRNA. Translation: CCF23108.1 .
    RefSeqi NP_004364.2. NM_004373.3.
    UniGenei Hs.369624.

    3D structure databases

    ProteinModelPortali H6SG15.
    SMRi H6SG15. Positions 25-107.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi H6SG15.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1337.
    KEGGi hsa:1337.

    Organism-specific databases

    CTDi 1337.

    Phylogenomic databases

    KOi K02266.
    OMAi REKRFPW.
    PhylomeDBi H6SG15.

    Miscellaneous databases

    ChiTaRSi COX6A1. human.
    GenomeRNAii 1337.
    NextBioi 5431.

    Gene expression databases

    Bgeei H6SG15.

    Family and domain databases

    Gene3Di 4.10.95.10. 1 hit.
    InterProi IPR001349. Cyt_c_oxidase_su6a.
    IPR018507. Cyt_c_oxidase_su6a_CS.
    [Graphical view ]
    PANTHERi PTHR11504. PTHR11504. 1 hit.
    Pfami PF02046. COX6A. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000277. COX6A1. 1 hit.
    ProDomi PD006036. Cyt_c_oxidase_su6a. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF81411. SSF81411. 1 hit.
    PROSITEi PS01329. COX6A. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-resolution melting analysis of 15 genes in 60 patients with cytochrome c oxidase deficiency."
      Vondrackova A., Vesela K., Hansikova H., Zajicova Docekalova D., Rozsypalova E., Zeman J., Tesarova M.
      Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Peripheral bloodImported.

    Entry informationi

    Entry nameiH6SG15_HUMAN
    AccessioniPrimary (citable) accession number: H6SG15
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.