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Protein

Superoxide dismutase

Gene

sodA

Organism
Mycobacterium tuberculosis UT205
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodAImported
ORF Names:UDA_3846Imported
OrganismiMycobacterium tuberculosis UT205Imported
Taxonomic identifieri1097669 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000007521: Chromosome

Structurei

3D structure databases

ProteinModelPortaliH6SB74.
SMRiH6SB74. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

KOiK04564.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H6SB74-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEYTLPDLD WDYGALEPHI SGQINELHHS KHHATYVKGA NDAVAKLEEA
60 70 80 90 100
RAKEDHSAIL LNEKNLAFNL AGHVNHTIWW KNLSPNGGDK PTGELAAAIA
110 120 130 140 150
DAFGSFDKFR AQFHAAATTV QGSGWAALGW DTLGNKLLIF QVYDHQTNFP
160 170 180 190 200
LGIVPLLLLD MWEHAFYLQY KNVKVDFAKA FWNVVNWADV QSRYAAATSQ

TKGLIFG
Length:207
Mass (Da):23,034
Last modified:April 18, 2012 - v1
Checksum:iDEE8F5921DABE54A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE608151 Genomic DNA. Translation: CCE39270.1.
RefSeqiYP_005310069.1. NC_016934.1.

Genome annotation databases

EnsemblBacteriaiCCE39270; CCE39270; UDA_3846.
GeneIDi13110349.
KEGGimtd:UDA_3846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE608151 Genomic DNA. Translation: CCE39270.1.
RefSeqiYP_005310069.1. NC_016934.1.

3D structure databases

ProteinModelPortaliH6SB74.
SMRiH6SB74. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCE39270; CCE39270; UDA_3846.
GeneIDi13110349.
KEGGimtd:UDA_3846.

Phylogenomic databases

KOiK04564.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome shotgun sequencing of one Colombian clinical isolate of Mycobacterium tuberculosis reveals DosR regulon gene deletions."
    Isaza J.P., Duque C., Gomez V., Robledo J., Barrera L.F., Alzate J.F.
    FEMS Microbiol. Lett. 330:113-120(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UT205Imported.

Entry informationi

Entry nameiH6SB74_MYCTX
AccessioniPrimary (citable) accession number: H6SB74
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: January 7, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.