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H6RLM3 (H6RLM3_BLASD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:ligB2 EMBL CCG03749.1
Synonyms:lig HAMAP-Rule MF_00407
Ordered Locus Names:BLASA_2878 EMBL CCG03749.1
OrganismBlastococcus saxobsidens (strain DD2) [Complete proteome] [HAMAP] EMBL CCG03749.1
Taxonomic identifier1146883 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeGeodermatophilaceaeBlastococcus

Protein attributes

Sequence length515 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2121N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2101ATP By similarity HAMAP-Rule MF_00407
Binding site2171ATP By similarity HAMAP-Rule MF_00407
Binding site2321ATP By similarity HAMAP-Rule MF_00407
Binding site2611ATP By similarity HAMAP-Rule MF_00407
Binding site3021ATP By similarity HAMAP-Rule MF_00407
Binding site3781ATP By similarity HAMAP-Rule MF_00407
Binding site3841ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
H6RLM3 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 1FBED4B2B38F3F32

FASTA51554,233
        10         20         30         40         50         60 
MLLAEVVAAS TAVAAARGRK AKAGLIAGAL RLADGDEVPA VTAWLSGEPL QRRLGIGWRS 

        70         80         90        100        110        120 
LAALTGGAAA ESTLTVADVD AAFAELATTS GPGSAARREE LLRGVLSRAT SEEQRFLVRL 

       130        140        150        160        170        180 
ITGELRQGAL EGVVLEAVAT ASGVPAADVR RAFMLSGSLP DTATAALRGG AEALSAISLQ 

       190        200        210        220        230        240 
VGRPVRPMLA GPGSSLDAAL ADLGPDVTVE FKLDGARVQV HRDGNQVRVW TRTLREVTDG 

       250        260        270        280        290        300 
VPELVERVRA LPCRTAVLDG ETLALDDDGR PRAFQDTMSR FGSAGAGGEM PDAGVLLSPF 

       310        320        330        340        350        360 
FFDLLHLDGR DLLDEPLDIR LDALAGLLAD DASAPLRMPG VRRPRPGQAA QVLEHALDAG 

       370        380        390        400        410        420 
HEGVVVKDLA APYAAGRRGK AWQKVKPVHT LDLVVLGAEW GYGRRTGTLS NIHLGARDPD 

       430        440        450        460        470        480 
GGEPVMVGKT FKGMTDELLA WQTRTFPEHT REETPWGVLL EPALVVEIAV DGAQRSPRYP 

       490        500        510 
GGVALRFARV LRYRPDKTPA EADTLEAVRA LLAGG 

« Hide

References

[1]"Complete genome sequence of Blastococcus saxobsidens strain DD2."
Genoscope.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DD2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO117623 Genomic DNA. Translation: CCG03749.1.
RefSeqYP_005329780.1. NC_016943.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCG03749; CCG03749; BLASA_2878.
GeneID11918476.
KEGGbsd:BLASA_2878.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01971.
OMAGRPRPFQ.

Enzyme and pathway databases

BioCycBSAX1146883:GL9E-2786-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH6RLM3_BLASD
AccessionPrimary (citable) accession number: H6RLM3
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: February 19, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)