H6RCV8 (H6RCV8_NOCCG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL CCF61408.1
Ordered Locus Names:	NOCYR_0593 EMBL CCF61408.1

Organism

Nocardia cyriacigeorgica (strain GUH-2) [Complete proteome] [HAMAP] EMBL CCF61408.1

Taxonomic identifier

1127134 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia › Nocardia cyriacigeorgica

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. SAAS SAAS004733 RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. SAAS SAAS004733 RuleBase RU004371
Subcellular location	Cytoplasm By similarity SAAS SAAS004733.
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS004733
Cellular component	Cytoplasm SAAS SAAS004733
Ligand	ATP-binding SAAS SAAS004733 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004733 RuleBase RU004370
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H6RCV8 [UniParc]. Last modified April 18, 2012. Version 1. Checksum: 165568EEF65BCB19	FASTA	359	37,408
	10 20 30 40 50 60 MSEQTPSGAG ASYAAAGVDI EAGDRAVELF APLARKASRP EVQGGLGGFA GLFALKGGYK 70 80 90 100 110 120 EPLLAASTDG VGTKIAVAQA MDKHDTVGLD LVAMVVDDLV VCGAEPLFLQ DYIAVGKVVP 130 140 150 160 170 180 ERVAELVSGI ADGCVRAGCA LLGGETAEHP GLMDPDDYDL SATGVGVVEA DAVLGPERVR 190 200 210 220 230 240 PGDVVIAMGS SGLHSNGYSL ARKVLLDIDR MSLTGHVEEF GRTLGEELLE PTRIYAKDCL 250 260 270 280 290 300 ALIAETDVRT FAHVTGGGLA ANLARVLPAG LVAELDRGTW NPAPVFKMIA QRGRVERPEM 310 320 330 340 350 EKTFNMGVGM VAVVAPEDVD RALAVLTARH IECWTLGTVT KAKDAGAPRA VMVGEHPRF

References

[1]

"Genome sequence of the human- and animal-pathogenic strain Nocardia cyriacigeorgica GUH-2." Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L., Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S., Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V., Richard Y., Cournoyer B., Blaha D. J. Bacteriol. 194:2098-2099(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GUH-2 EMBL CCF61408.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO082843 Genomic DNA. Translation: CCF61408.1.
RefSeq	YP_005262052.1. NC_016887.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CCF61408; CCF61408; NOCYR_0593.
GeneID	11925490.
KEGG	ncy:NOCYR_0593.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01933.
Enzyme and pathway databases
UniPathway	UPA00074; UER00129.
Family and domain databases
InterPro	IPR010918. AIR_synth_C_dom. IPR000728. AIR_synth_N_dom. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. purM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

H6RCV8_NOCCG

Accession

Primary (citable) accession number: H6RCV8

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2012
Last sequence update:	April 18, 2012
Last modified:	April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)