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H6R058

- H6R058_NOCCG

UniProt

H6R058 - H6R058_NOCCG

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Nocardia cyriacigeorgica (strain GUH-2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei160 – 1601UniRule annotation
Active sitei622 – 6221UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciNCYR1127134:GLHX-2132-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:NOCYR_2139Imported
OrganismiNocardia cyriacigeorgica (strain GUH-2)Imported
Taxonomic identifieri1127134 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000008190: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H6R058-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFGNLRQYCR NMTEPRIETE QDATRPLRED IRFLGGVLGD TIRDHEGPEV
60 70 80 90 100
FDLIERVRVE AFRVRREEVG RSAVADMLDG VDITVALPLI RAFSYFVLLA
110 120 130 140 150
NLAEDLQRDR RREAHEAAGE PPQDSSLAAT YRKLDAAALP EAKVAELLTD
160 170 180 190 200
ALVSPVITAH PTETRRRTVF DVQTKITELM RRRRHYPERD RAGLELEIRR
210 220 230 240 250
QVLTLWRTAL IRLARLRIQD EIAVGLRYYE LTLFDVIPAI NAEVRAALRS
260 270 280 290 300
RWPDADLLPR PILRPGSWIG GDRDGNPYVT AEVVRTAAGQ AAGVAFGRYL
310 320 330 340 350
RDLVELEKTL SQSGRLVQVS ATVAELAAAG YADPNVHADE PYRRALHRIR
360 370 380 390 400
ERLTTTAEQA LGVPIRSTGA PALGAAAELG ATPIPAVPAL GAPDTTTATP
410 420 430 440 450
APAYPGPQAL LDDLDAIDAS LRDSGDGLLA DDRLAALRHA VETFGFHLQG
460 470 480 490 500
LDMRQNSEVH EQVVAELLAW AGVHPDYASL PEPERVRILS TELSTRRPLL
510 520 530 540 550
GPHARLSELA AKELGIVRAA ADVVATFGEP AIPNYIISMC TSVSDMLEAA
560 570 580 590 600
LLLKEGGLLD PGAPDGSPSC AAGIVPLFET IEDLGAGAAT LAAVLEVPVY
610 620 630 640 650
RELVAAKGMR QEVMLGYSDS NKDGGYLAAN WALYRAELDL VEVARKTGIR
660 670 680 690 700
LRLFHGRGGT VGRGGGRSYD AILAQPAGAV HGSLRLTEQG EVIAAKYAES
710 720 730 740 750
GSAHRNLESL IAGTLESTLL DMEGLGADAE PSYQLMDELA ARARAAYARL
760 770 780 790 800
VHETPGFVEY FRQSTPVAEV GDLNIGSRPA SRKPTNSVAD LRAIPWVMSW
810 820 830 840 850
SQARVMLPGW YGTGTALEEW VDDDPQRLAT LADLYRRWPF FRTVLSNLAQ
860 870 880 890 900
VMAKSDLAIA ARYAELVEDT ALREHIFGMI RDEHARTIRM HAAITGNDHL
910 920 930 940 950
LSDNPSLAES IRNRFPYLEP LNQMQVELLR RLRAGDDSEL VKRGILLTMN
960
GLATALRNSG
Length:960
Mass (Da):104,997
Last modified:April 18, 2012 - v1
Checksum:iB6F713534C8C6868
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO082843 Genomic DNA. Translation: CCF62921.1.
RefSeqiYP_005263557.1. NC_016887.1.

Genome annotation databases

EnsemblBacteriaiCCF62921; CCF62921; NOCYR_2139.
GeneIDi11927025.
KEGGincy:NOCYR_2139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO082843 Genomic DNA. Translation: CCF62921.1 .
RefSeqi YP_005263557.1. NC_016887.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCF62921 ; CCF62921 ; NOCYR_2139 .
GeneIDi 11927025.
KEGGi ncy:NOCYR_2139.

Phylogenomic databases

KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci NCYR1127134:GLHX-2132-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 2 hits.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GUH-2Imported.

Entry informationi

Entry nameiH6R058_NOCCG
AccessioniPrimary (citable) accession number: H6R058
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 26, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3