Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

H6QD97 (H6QD97_PYROT) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617 HAMAP-Rule MF_00407

EC=6.5.1.1 RuleBase RU000617 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Pogu_2413 EMBL AFA40440.1
OrganismPyrobaculum oguniense (strain DSM 13380 / JCM 10595 / TE7) [Complete proteome] [HAMAP] EMBL AFA40440.1
Taxonomic identifier698757 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum

Protein attributes

Sequence length584 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617 HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2511N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2491ATP By similarity HAMAP-Rule MF_00407
Binding site2561ATP By similarity HAMAP-Rule MF_00407
Binding site2711ATP By similarity HAMAP-Rule MF_00407
Binding site3011ATP By similarity HAMAP-Rule MF_00407
Binding site3411ATP By similarity HAMAP-Rule MF_00407
Binding site4161ATP By similarity HAMAP-Rule MF_00407
Binding site4221ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
H6QD97 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: E5066712F05608AF

FASTA58464,776
        10         20         30         40         50         60 
MQFGELVKAL AAVESTTQRS VMVKLLASLF KKALPEEIDK VIYLILGDLR PPWEGLELGV 

        70         80         90        100        110        120 
GEKLCLRALA KATGTSQAEL ESLYKKTGDI GEAARRSLAS SKRPGLLTFG SQKPLEVSEV 

       130        140        150        160        170        180 
YDTLLKVARA SGEGAQDMKI ALLSSLFARS SPEEGKYIAR FVVGKLRLGV ADMTIIEALA 

       190        200        210        220        230        240 
DAYGVRKEDL ERAYHVYPDL GHLAKLVASG KPLDEVKVTP GVPVLPMLAQ RLSSSSEILA 

       250        260        270        280        290        300 
KLGGTAICEY KYDGERAQIH ISQSGVRIFS RRLEDITHAY PDVVKAVKEA VMAREAILEG 

       310        320        330        340        350        360 
EIVAVDPDTG EMLPFQELMH RKRKHEVVAA MEMYPTVLYL FDVIFVDGED LTNEPLIYRR 

       370        380        390        400        410        420 
VKLSEIVQES DKVQIAKWLM LDDPDSVDVF FHEAVSVGTE GLICKSPTSE YEMGARGWNW 

       430        440        450        460        470        480 
IKYKRDYKSE MIDTVDLVVV GAFYGRGKRA GLYGAFLLAA YDPSSDMFYT VCKVGSGFTD 

       490        500        510        520        530        540 
ADLKKMYEIL QPLKIPHRHP RVSSKMEADV WFVPQVVIEV IGAEITLSPL HTCCLGAVRP 

       550        560        570        580 
GVGLAVRFPR FTGRYRTDKG PEQATTVAEM LELYKRQKKV AQPE 

« Hide

References

[1]"Complete genome sequence of Pyrobaculum oguniense."
Bernick D.L., Karplus K., Lui L.M., Coker J.K.C., Murphy J.N., Cozen A.E., Chan P.P., Lowe T.M.
Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13380 / JCM 10595 / TE7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003316 Genomic DNA. Translation: AFA40440.1.
RefSeqYP_005261047.1. NC_016885.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFA40440; AFA40440; Pogu_2413.
GeneID11856308.
KEGGpog:Pogu_2413.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.
OMAYIARFVV.

Enzyme and pathway databases

BioCycPOGU698757:GHQD-2563-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH6QD97_PYROT
AccessionPrimary (citable) accession number: H6QD97
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: February 19, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)