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H6PLK6 (H6PLK6_RICRI) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2491Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1331Substrate By similarity HAMAP-Rule MF_01201
Binding site2971Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
H6PLK6 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 7DD4604AEBF6030A

FASTA35539,501
        10         20         30         40         50         60 
MSLCTVEINL STIKNNYLLL QDVCKTSLVG AAVKANGYGL GAIQISKALI EENCRHFFVA 

        70         80         90        100        110        120 
SSEEGVNLRN ALGLDINILV LNGVFEHDAL ELIEYNLTPV LNNLKQIEIW QKFSNLKNRL 

       130        140        150        160        170        180 
LPCYLHFNTG INRLGLSSDE IEQLINDRDL LKGLDLQYII SHLAISEEID NPYNLEQLNR 

       190        200        210        220        230        240 
FKAYLQYFPN VKASLANSGG IFLGQDYHFD LARPGAALYG LNPLTKNPVT LKAPIIHLQN 

       250        260        270        280        290        300 
LTLDSHIGYN MTFTTKRDSV IATLPLGYAD GFSRNFSNQG EVFINSRSVP IVGRVSMDLI 

       310        320        330        340        350 
NIDVTDLPPS EIFLGQEAEI IGNYCTPNKI ASIIGTIGYE VLTNLGSRYK RKYIG 

« Hide

References

[1]Johnson S.L., Munk A.C., Han S., Bruce D.C., Dasch G.A.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Colombia EMBL AFB23066.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003306 Genomic DNA. Translation: AFB23066.1.
RefSeqYP_005285690.1. NC_016908.1.

3D structure databases

ProteinModelPortalH6PLK6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFB23066; AFB23066; RPL_00735.
GeneID11785510.
KEGGrrc:RPL_00735.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycRRIC1105102:GJU0-138-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH6PLK6_RICRI
AccessionPrimary (citable) accession number: H6PLK6
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: July 9, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)