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Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Streptococcus infantarius (strain CJ18)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciSINF1069533:GLL3-655-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:Sinf_0582Imported
OrganismiStreptococcus infantarius (strain CJ18)Imported
Taxonomic identifieri1069533 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008191 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliH6P9J2.
SMRiH6P9J2. Positions 2-391.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H6P9J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKITLENG QLVVSNHPII PFIEGDGVGR DIWKNARAVF DAAVEKAYQG
60 70 80 90 100
QKKVEWHELL AGKKAHEATG KWLPEETLDT IKKDLIAIKG PLETPVGGGI
110 120 130 140 150
RSLNVTLRQE LDLYACVRPV RYFKGIESPL KEPEKTSITI FRENTEDIYA
160 170 180 190 200
GIEWEAGTPE VKKVIEFLQN DMSVSKIRFP ETSSIGIKPI SKEGSERLIR
210 220 230 240 250
SAIEYALANH LTNVTIVHKG NIQKFTEGGF RKWGYELAER EYADELASGK
260 270 280 290 300
LVMNDIIADN FLQQILLNPE KFDVVALTNL NGDYASDALA AQVGGIGISP
310 320 330 340 350
GANINYVTGH AIFEATHGTA PDIAGKDIAN PCSVLLSGCM LFDYIGWTEV
360 370 380 390
ASLISQAIEK TFAKGQFTAD LAQGKAACST SEFAAKLIEN M
Length:391
Mass (Da):42,787
Last modified:April 18, 2012 - v1
Checksum:i2EB2C8548C4C69EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003295 Genomic DNA. Translation: AEZ61933.1.
RefSeqiWP_006532303.1. NC_016826.1.
YP_005203404.1. NC_016826.1.

Genome annotation databases

EnsemblBacteriaiAEZ61933; AEZ61933; Sinf_0582.
GeneIDi11877104.
KEGGisif:Sinf_0582.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003295 Genomic DNA. Translation: AEZ61933.1.
RefSeqiWP_006532303.1. NC_016826.1.
YP_005203404.1. NC_016826.1.

3D structure databases

ProteinModelPortaliH6P9J2.
SMRiH6P9J2. Positions 2-391.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEZ61933; AEZ61933; Sinf_0582.
GeneIDi11877104.
KEGGisif:Sinf_0582.

Phylogenomic databases

KOiK00031.

Enzyme and pathway databases

BioCyciSINF1069533:GLL3-655-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the African dairy isolate Streptococcus infantarius subsp. infantarius strain CJ18."
    Jans C., Follador R., Lacroix C., Meile L., Stevens M.J.
    J. Bacteriol. 194:2105-2106(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CJ18Imported.

Entry informationi

Entry nameiH6P9J2_STRIC
AccessioniPrimary (citable) accession number: H6P9J2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 1, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.