H6P131 (H6P131_SALTI) Unreviewed, UniProtKB/TrEMBL
Last modified
April 3, 2013.
Version 10.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Lysine--tRNA ligase RuleBase RU000336 HAMAP-Rule MF_00252 EC=6.1.1.6 RuleBase RU000336 HAMAP-Rule MF_00252 Alternative name(s): Lysyl-tRNA synthetase HAMAP-Rule MF_00252 | ||||
| Gene names |
| ||||
| Organism | Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12 EMBL AEZ46759.1 | ||||
| Taxonomic identifier | 1132507 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › ![]() |
Protein attributes
| Sequence length | 505 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). RuleBase RU000336 HAMAP-Rule MF_00252 SAAS SAAS002313 |
| Cofactor | Binds 3 magnesium ions per subunit By similarity. RuleBase RU000336 HAMAP-Rule MF_00252 |
| Subunit structure | Homodimer By similarity. HAMAP-Rule MF_00252 SAAS SAAS002313 |
| Subcellular location | Cytoplasm By similarity HAMAP-Rule MF_00252. |
| Sequence similarities | Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00252 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Protein biosynthesis HAMAP-Rule MF_00252 SAAS SAAS002313 |
| Cellular component | Cytoplasm HAMAP-Rule MF_00252 SAAS SAAS002313 |
| Ligand | ATP-binding SAAS SAAS002313 HAMAP-Rule MF_00252 Magnesium RuleBase RU000336 HAMAP-Rule MF_00252 SAAS SAAS002313 Metal-binding RuleBase RU000336 HAMAP-Rule MF_00252 SAAS SAAS002313 Nucleotide-binding |
| Molecular function | Aminoacyl-tRNA synthetase HAMAP-Rule MF_00252 SAAS SAAS002313 EMBL AEZ46759.1 Ligase |
| Gene Ontology (GO) | |
| Biological_process | lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activityInferred from electronic annotation. Source: HAMAP magnesium ion bindingInferred from electronic annotation. Source: HAMAP nucleic acid bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Metal binding | 415 | 1 | Magnesium 1 By similarity HAMAP-Rule MF_00252 | ||||||
| Metal binding | 422 | 1 | Magnesium 1 By similarity HAMAP-Rule MF_00252 | ||||||
| Metal binding | 422 | 1 | Magnesium 2 By similarity HAMAP-Rule MF_00252 | ||||||
Sequences
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References
| [1] | "Complete Genome Sequence of Salmonella enterica subsp. enterica Serovar Typhi P-stx-12." Ong S.Y., Pratap C.B., Wan X., Hou S., Abdul Rahman A.Y., Saito J.A., Nath G., Alam M. J. Bacteriol. 194:2115-2116(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: P-stx-12 EMBL AEZ46759.1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP003278 Genomic DNA. Translation: AEZ46759.1. |
| RefSeq | YP_005218612.1. NC_016832.1. |
3D structure databases | |
| ProteinModelPortal | H6P131. |
| SMR | H6P131. Positions 12-503. |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | H6P131. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AEZ46759; AEZ46759; STBHUCCB_31170. |
| GeneID | 11821610. |
| KEGG | sex:STBHUCCB_31170. |
Phylogenomic databases | |
| KO | K04567. |
| OMA | EHKLEQP. |
Family and domain databases | |
| Gene3D | 2.40.50.140. 1 hit. |
| HAMAP | MF_00252. Lys_tRNA_synth_class2. |
| InterPro | IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR002313. Lys-tRNA-ligase_II. IPR018149. Lys-tRNA-synth_II_C. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view] |
| PANTHER | PTHR22594. PTHR22594. 1 hit. PTHR22594:SF4. PTHR22594:SF4. 1 hit. |
| Pfam | PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view] |
| PRINTS | PR00982. TRNASYNTHLYS. |
| SUPFAM | SSF50249. Nucleic_acid_OB. 1 hit. |
| TIGRFAMs | TIGR00499. lysS_bact. 1 hit. |
| PROSITE | PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | H6P131_SALTI | ||||||||
| Accession | Primary (citable) accession number: H6P131 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
