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H6N3M1 (H6N3M1_GORPV) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase [NADP] Icd EMBL AFA73492.1
EC=1.1.1.42 EMBL AFA73492.1
Gene names
Name:icd EMBL AFA73492.1
Ordered Locus Names:GPOL_c24630 EMBL AFA73492.1
OrganismGordonia polyisoprenivorans (strain DSM 44266 / VH2) [Complete proteome] [HAMAP] EMBL AFA73492.1
Taxonomic identifier1112204 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Gordoniaceae › Gordonia ›

Protein attributes

Sequence length745 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5511Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5551Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5501Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4221Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
H6N3M1 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 8492FCB219E0DCE2

FASTA74582,445
        10         20         30         40         50         60 
MSAEKPTIIY TLTDEAPMLA THAFLPIIRT FADAADINVE TSDISVAARV LAEFSDYLSD 

        70         80         90        100        110        120 
EQKVPDNLAE LGRLTQDPDT NIIKLPNISA SVPQLTAAIK ELQDKGYKIP DFPGNPKTDE 

       130        140        150        160        170        180 
ERAIRDRYTK CLGSAVNPVL REGNSDRRAP KAVKEYARKH PHSMGEWSMA SRTHVAHMRH 

       190        200        210        220        230        240 
GDFYHGEKSM TLDADRDVKM ELITAAGETI VLKPKVHLDA GDVIDSMFMS KKALIEFYEE 

       250        260        270        280        290        300 
QMEDAYKTGV MFSLHVKATM MRVSHPIVFG HAVRTFYKEA FAKHGELFDE LGVNVNNGLS 

       310        320        330        340        350        360 
DLYSKIESLP ASKKEEIIDD LHACHEHRPE LAMVDSARGI SNFHSPSDVI VDASMPAMIR 

       370        380        390        400        410        420 
AGGKMYGADG RPKDTKAVNP ESTFSRIYQE MINFCKTNGQ FDPTTMGTVP NVGLMAQKAE 

       430        440        450        460        470        480 
EYGSHDKTFE IPTDGVANIT DLATGEVLLS QDVEEGDIFR MCIVKDAPIR DWVKLAVTRS 

       490        500        510        520        530        540 
RESGMPVVFW LDPYRPHENE LITKVHTYLK DHDTEGLDIQ IMSQVRAIRY TMERLIRGLD 

       550        560        570        580        590        600 
TISATGNILR DYLTDLFPIL ELGTSAKMLS IVPLMAGGGL YETGAGGSAP KHVKQLIEEN 

       610        620        630        640        650        660 
HLRWDSLGEF LALAVSLEDL GRKNDNPKAK VLAKALDAAT GKLLENNKGP SRSTGELDNR 

       670        680        690        700        710        720 
GSQFYLALYW AKALAEQTED ADLAKYFAPL AKTLEENEQT IVAELNDVQG TAVDIGGYYA 

       730        740 
PDNDLTDKVM RPSATLNSAL ESVRG

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References

[1]"Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2."
Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A., Liebl W., Daniel R., Steinbuchel A.
Appl. Environ. Microbiol. 78:2874-2887(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 44266 / VH2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003119 Genomic DNA. Translation: AFA73492.1.
RefSeqYP_005282858.1. NC_016906.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFA73492; AFA73492; GPOL_c24630.
GeneID11782471.
KEGGgpo:GPOL_c24630.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameH6N3M1_GORPV
AccessionPrimary (citable) accession number: H6N3M1
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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