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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Gordonia polyisoprenivorans (strain DSM 44266 / VH2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei167 – 1671UniRule annotation
Active sitei605 – 6051UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciGPOL1112204:GJWY-2275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:GPOL_c22780Imported
OrganismiGordonia polyisoprenivorans (strain DSM 44266 / VH2)Imported
Taxonomic identifieri1112204 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeGordoniaceaeGordonia
ProteomesiUP000009154: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H6N0U8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPSRGAPD WRPSISIVDH IVVDDEGRTL TEPLREDIRL LGGILGDMVR
60 70 80 90 100
EHSGAEVFDL VESARVAAFK IRRAEIDRDE LADLFVDLDI SVAMPIIRAF
110 120 130 140 150
SNFALLANLA EDIHRERRRM IHVRAGDPPQ DSSLDATYAK LAEAGLGDDE
160 170 180 190 200
VGDALADATV VPVITAHPTE TRRRSVFEAQ NRITELMRYR SRTELTPAEE
210 220 230 240 250
AAVTEGIRRQ ILTLWQTALI RLERLTIQDE IRSGLRYYDA SFFEVVPKIN
260 270 280 290 300
TSVRAALRSA YPNAGLADEP MLRMGSWIGG DRDGNPFVTG EIVEMATTLA
310 320 330 340 350
ARTAIGNHLS ELEALAQELS MSTRLMTTSD AVYELAGVPR EDAAADEPFR
360 370 380 390 400
LALRHIRSRL VATATGLFGE EVMKTSDLFL LDGADAYSTA DELLADLDVI
410 420 430 440 450
DAGLRAANDD IIADDRLLRL RESVRTFGFH LSGLDMRQNS DMHEDVIAEL
460 470 480 490 500
LAWAGVHPDY RSLDEAERVE ILTNELAARR PLTRPDAELS ELATKELNIV
510 520 530 540 550
RAAATAVARF GPQSVPNYII SMCTSVSDML EPMILLKEAG LIDIDGDTGK
560 570 580 590 600
LISTVRIVPL FETIEDLQQG AETLLAALDI PLYRDLVDGQ SGMQEVMLGY
610 620 630 640 650
SDSNKDGGYM AANWALYRGE LDLVEAAAKA GIRLRLFHGR GGTVGRGGGP
660 670 680 690 700
SYDAILAQPP GAVQGSLRIT EQGEIIAAKY AEPVSAERNL ETLLAATIES
710 720 730 740 750
SLLDVEGLGD ESEDAYTTLD EIAALARSAY SALVHETPGF VEYFTTSTPL
760 770 780 790 800
SEIGALNIGS RPASRKQTEK ISDLRAIPWV LSWTQSRVML PGWYGTGAAF
810 820 830 840 850
EQWVGDDADR LATLQRYYEK WPFFRTVMSN MAQVLAKSDM GLAHRYAQLV
860 870 880 890 900
PDEQLRDTVF GMIVDEHERT IAMYSKITGT NDLLADNAAL KRSVYNRFPY
910 920 930 940
LEPLNLLQVE LLRRFRAGDD SPRIRRGIQL TMNGLATALR NSG
Length:943
Mass (Da):103,898
Last modified:April 18, 2012 - v1
Checksum:iF59AD5B34C12A027
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003119 Genomic DNA. Translation: AFA73310.1.
RefSeqiWP_006370297.1. NC_016906.1.
YP_005282676.1. NC_016906.1.

Genome annotation databases

EnsemblBacteriaiAFA73310; AFA73310; GPOL_c22780.
GeneIDi11782287.
KEGGigpo:GPOL_c22780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003119 Genomic DNA. Translation: AFA73310.1.
RefSeqiWP_006370297.1. NC_016906.1.
YP_005282676.1. NC_016906.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFA73310; AFA73310; GPOL_c22780.
GeneIDi11782287.
KEGGigpo:GPOL_c22780.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciGPOL1112204:GJWY-2275-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2."
    Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A., Liebl W., Daniel R., Steinbuchel A.
    Appl. Environ. Microbiol. 78:2874-2887(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 44266 / VH2Imported.

Entry informationi

Entry nameiH6N0U8_GORPV
AccessioniPrimary (citable) accession number: H6N0U8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: March 4, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.