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H6M557

- H6M557_CORPS

UniProt

H6M557 - H6M557_CORPS

Protein
Submitted name:

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Corynebacterium pseudotuberculosis 316
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei143 – 1431SubstrateUniRule annotation
    Sitei252 – 2521Critical for catalysisUniRule annotation
    Metal bindingi345 – 3451Magnesium or manganeseUniRule annotation
    Sitei415 – 4151Critical for catalysisUniRule annotation
    Binding sitei542 – 5421SubstrateUniRule annotation
    Metal bindingi543 – 5431Magnesium or manganeseUniRule annotation
    Metal bindingi547 – 5471Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciCPSE1074485:GLBT-496-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase [NADP]Imported
    Gene namesi
    Name:icdImported
    ORF Names:Cp316_0480Imported
    OrganismiCorynebacterium pseudotuberculosis 316Imported
    Taxonomic identifieri1074485 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000008009: Chromosome

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni130 – 1378Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    H6M557-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKIIYTRTD EAPLLATYSL KPVVEAFAST AGIEVETRDI SLAGRILSQF    50
    PEFLTEDQKV EDALAELGEL AKTPEANIIK LPNISASVPQ LKAAVTELQS 100
    QGYKLPDYPD SPSTEEEKDI RARYDAVKGS AVNPVLREGN SDRRAPIAVK 150
    NFAKKHPHRM GAWSADSKTN VVTMESNDFR HNEKSVIIPD NDTLTIKLVT 200
    DNGEKVLKDG LKVLKGEVVD GTFISARALD EFLADQVKRA KDEGVLFSAH 250
    LKATMMKVSD PIIFGHVVRA YFADVFAKYG EQLEAAGLNG ENGLAAIYSG 300
    LESLPNGTEI KAAFDEALES GADIAMVNSA KGITNLHVPS DVIIDASMPA 350
    MIRTSGHMWN KNDEEQDTLA VIPDSSYAGV YQTVIADCKK NGAFDPTTMG 400
    TVPNVGLMAQ KAEEYGSHDK TFKIEANGTV QVVSSAGEVL IEHNVEAGDI 450
    WRACQAKDAP IQDWVKLAVT RSRLSGMPAV FWLDPERAHD RNLAALVEKY 500
    LADHDTEGLD IHIMSPVEAT QFSIDRIRRG EDTISVTGNV LRDYNTDLFP 550
    ILELGTSAKM LSVVPLMAGG GLFETGAGGS APKHVQQLVE ENHLRWDSLG 600
    EFLALAESLR HFANTEGNTK AGILADTLDR ATETLLNEGY SPSRKAGEID 650
    NRGSHFFLTK FWAKELSIQS EDADLAATFT PVAEALETHS EDIADALLAV 700
    QGTPADLGGY YHPDDAKTTA VMRPVASYND IISSIK 736
    Length:736
    Mass (Da):79,873
    Last modified:April 18, 2012 - v1
    Checksum:iAF23E678C43123CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003077 Genomic DNA. Translation: AFB71802.1.
    RefSeqiWP_014366573.1. NC_016932.1.
    YP_005303084.1. NC_016932.1.

    Genome annotation databases

    EnsemblBacteriaiAFB71802; AFB71802; Cp316_0480.
    GeneIDi11891839.
    KEGGicpg:Cp316_0480.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003077 Genomic DNA. Translation: AFB71802.1 .
    RefSeqi WP_014366573.1. NC_016932.1.
    YP_005303084.1. NC_016932.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFB71802 ; AFB71802 ; Cp316_0480 .
    GeneIDi 11891839.
    KEGGi cpg:Cp316_0480.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci CPSE1074485:GLBT-496-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 316Imported.

    Entry informationi

    Entry nameiH6M557_CORPS
    AccessioniPrimary (citable) accession number: H6M557
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3