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H6M557

- H6M557_CORPS

UniProt

H6M557 - H6M557_CORPS

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Protein
Submitted name: Isocitrate dehydrogenase [NADP]
Gene
icd, Cp316_0480
Organism
Corynebacterium pseudotuberculosis 316
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei143 – 1431Substrate By similarityUniRule annotation
Sitei252 – 2521Critical for catalysis By similarityUniRule annotation
Metal bindingi345 – 3451Magnesium or manganese By similarity
Sitei415 – 4151Critical for catalysis By similarityUniRule annotation
Binding sitei542 – 5421Substrate By similarityUniRule annotation
Metal bindingi543 – 5431Magnesium or manganese By similarity
Metal bindingi547 – 5471Magnesium or manganese By similarity

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCPSE1074485:GLBT-496-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP]Imported
Gene namesi
Name:icdImported
ORF Names:Cp316_0480Imported
OrganismiCorynebacterium pseudotuberculosis 316Imported
Taxonomic identifieri1074485 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000008009: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1378Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

H6M557-1 [UniParc]FASTAAdd to Basket

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MAKIIYTRTD EAPLLATYSL KPVVEAFAST AGIEVETRDI SLAGRILSQF    50
PEFLTEDQKV EDALAELGEL AKTPEANIIK LPNISASVPQ LKAAVTELQS 100
QGYKLPDYPD SPSTEEEKDI RARYDAVKGS AVNPVLREGN SDRRAPIAVK 150
NFAKKHPHRM GAWSADSKTN VVTMESNDFR HNEKSVIIPD NDTLTIKLVT 200
DNGEKVLKDG LKVLKGEVVD GTFISARALD EFLADQVKRA KDEGVLFSAH 250
LKATMMKVSD PIIFGHVVRA YFADVFAKYG EQLEAAGLNG ENGLAAIYSG 300
LESLPNGTEI KAAFDEALES GADIAMVNSA KGITNLHVPS DVIIDASMPA 350
MIRTSGHMWN KNDEEQDTLA VIPDSSYAGV YQTVIADCKK NGAFDPTTMG 400
TVPNVGLMAQ KAEEYGSHDK TFKIEANGTV QVVSSAGEVL IEHNVEAGDI 450
WRACQAKDAP IQDWVKLAVT RSRLSGMPAV FWLDPERAHD RNLAALVEKY 500
LADHDTEGLD IHIMSPVEAT QFSIDRIRRG EDTISVTGNV LRDYNTDLFP 550
ILELGTSAKM LSVVPLMAGG GLFETGAGGS APKHVQQLVE ENHLRWDSLG 600
EFLALAESLR HFANTEGNTK AGILADTLDR ATETLLNEGY SPSRKAGEID 650
NRGSHFFLTK FWAKELSIQS EDADLAATFT PVAEALETHS EDIADALLAV 700
QGTPADLGGY YHPDDAKTTA VMRPVASYND IISSIK 736
Length:736
Mass (Da):79,873
Last modified:April 18, 2012 - v1
Checksum:iAF23E678C43123CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003077 Genomic DNA. Translation: AFB71802.1.
RefSeqiWP_014366573.1. NC_016932.1.
YP_005303084.1. NC_016932.1.

Genome annotation databases

EnsemblBacteriaiAFB71802; AFB71802; Cp316_0480.
GeneIDi11891839.
KEGGicpg:Cp316_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003077 Genomic DNA. Translation: AFB71802.1 .
RefSeqi WP_014366573.1. NC_016932.1.
YP_005303084.1. NC_016932.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFB71802 ; AFB71802 ; Cp316_0480 .
GeneIDi 11891839.
KEGGi cpg:Cp316_0480.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci CPSE1074485:GLBT-496-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 316Imported.

Entry informationi

Entry nameiH6M557_CORPS
AccessioniPrimary (citable) accession number: H6M557
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 3, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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