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H6M0H1 (H6M0H1_FRATL) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. SAAS SAAS020634 HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding87 – 904ATP By similarity HAMAP-Rule MF_00124

Sites

Active site881Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1871Zinc By similarity HAMAP-Rule MF_00124
Metal binding1901Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
H6M0H1 [UniParc].

Last modified April 18, 2012. Version 1.
Checksum: 5D38405A53232252

FASTA19722,429
        10         20         30         40         50         60 
MAKLYFRYSA MDAGKTLDLL KVAYNYEDRG RKPLVLTSAI DKRAGLNKVK SRIGINQDAY 

        70         80         90        100        110        120 
SLTDRDNIFE FVENYNSSNK IDCVLIDEIH FFTQEQVWQL AEIVDELNIP VICYGLRTNY 

       130        140        150        160        170        180 
LGQPFETAAL LLAIADTLEE VKTICHCGKK ASCNMMVQNG KAIKQGNPIV VDDDSLKEID 

       190 
TKYVSVCRKH WKEGVYE 

« Hide

References

[1]"Genomic Comparison between a Virulent Type A1 Strain of Francisella tularensis and Its Attenuated O-Antigen Mutant."
Modise T., Ryder C., Mane S.P., Bandara A.B., Jensen R.V., Inzana T.J.
J. Bacteriol. 194:2775-2776(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TI0902 EMBL AFB80297.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003049 Genomic DNA. Translation: AFB80297.1.
RefSeqYP_005317786.1. NC_016937.1.

3D structure databases

ProteinModelPortalH6M0H1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFB80297; AFB80297; FTV_0581.
GeneID11880729.
KEGGftt:FTV_0581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Enzyme and pathway databases

BioCycFTUL1001534:GLDI-590-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameH6M0H1_FRATL
AccessionPrimary (citable) accession number: H6M0H1
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 16, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)