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H6LTN3

- H6LTN3_FRATL

UniProt

H6LTN3 - H6LTN3_FRATL

Protein

Glutamate decarboxylase

Gene

gad

Organism
Francisella tularensis subsp. tularensis TIGB03
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciFTUL1001542:GLDJ-1772-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadImported
    ORF Names:FTU_1725Imported
    OrganismiFrancisella tularensis subsp. tularensis TIGB03Imported
    Taxonomic identifieri1001542 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000008010: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliH6LTN3.
    SMRiH6LTN3. Positions 13-435.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    H6LTN3-1 [UniParc]FASTAAdd to Basket

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    MALHGKKDTI DNLDFFEQSL PKFKLPLNSQ DPLEVYQEIK DELMLDGNSK    50
    QNLATFCQTE VDDFIHKLMD DCIDKNMIDK DEYPQTAEIE SRCVNILANL 100
    WNSSAENAIG CSTTGSSEAA MLGGMAMKWR WRDKMKAQGK DYTKPNLVTG 150
    PVQVCWHKFA RYWDIELREI PMSNESLIMT PEAVLERCDE NTIGVVPTLG 200
    VTFTGQYEPV EQVCKALDDF ERQTGVDIPV HVDAASGGFL APFVEPELKW 250
    DFRLPRVKSI NSSGHKFGLS PLGVGWVIWA DKKYLPDDLI FNVNYLGGNM 300
    PAFALNFSRL GGQIVAQYYN FVRLGFEGYK KVHQLCYDVA EYIAKELRKM 350
    EIFEIIHAGE GGIPAVSWSL KATKEYSLFD ISEKVRAKGW QIAAYTMPNN 400
    REDLVVMRVL VRRGFSYDLA QLMIRDLVAV IDSLEGKLKI LKRSSFAH 448
    Length:448
    Mass (Da):50,815
    Last modified:April 18, 2012 - v1
    Checksum:i2A48F8FD23CA64D4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003048 Genomic DNA. Translation: AFB79710.1.
    RefSeqiYP_005306290.1. NC_016933.1.

    Genome annotation databases

    EnsemblBacteriaiAFB79710; AFB79710; FTU_1725.
    GeneIDi11891272.
    KEGGiftg:FTU_1725.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003048 Genomic DNA. Translation: AFB79710.1 .
    RefSeqi YP_005306290.1. NC_016933.1.

    3D structure databases

    ProteinModelPortali H6LTN3.
    SMRi H6LTN3. Positions 13-435.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFB79710 ; AFB79710 ; FTU_1725 .
    GeneIDi 11891272.
    KEGGi ftg:FTU_1725.

    Phylogenomic databases

    KOi K01580.

    Enzyme and pathway databases

    BioCyci FTUL1001542:GLDJ-1772-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genomic Comparison between a Virulent Type A1 Strain of Francisella tularensis and Its Attenuated O-Antigen Mutant."
      Modise T., Ryder C., Mane S.P., Bandara A.B., Jensen R.V., Inzana T.J.
      J. Bacteriol. 194:2775-2776(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TIGB03Imported.

    Entry informationi

    Entry nameiH6LTN3_FRATL
    AccessioniPrimary (citable) accession number: H6LTN3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3