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H6LGV4

- H6LGV4_ACEWD

UniProt

H6LGV4 - H6LGV4_ACEWD

Protein

Elongation factor Tu

Gene

tuf

Organism
Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (18 Apr 2012)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi82 – 865GTPUniRule annotation
    Nucleotide bindingi137 – 1404GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAWOO931626:GI4Q-2865-MONOMER.
    AWOO931626:GI4Q-914-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Synonyms:tufBImported
    Ordered Locus Names:Awo_c09160Imported, Awo_c28670Imported
    OrganismiAcetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655)Imported
    Taxonomic identifieri931626 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeAcetobacterium
    ProteomesiUP000007177: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.
    OMAiRITISCE.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H6LGV4-1 [UniParc]FASTAAdd to Basket

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    MAKSKFERNK PHVNVGTIGH VDHGKTTLTA AITSVLNKRF GTGEAVAFEN    50
    IDKAPEERER GITISTAHVE YETATRHYAH VDCPGHADYV KNMITGAAQM 100
    DGAILVVSAA DGPMPQTREH ILLSRQVGVP YIIVFLNKVD MVDDEELLEL 150
    VEMEVRELLD EYDFPGDDTP IIAGSALKAL EDPDGPWGDK IVELMTAVDE 200
    WIPDPVRDTD KPFLMPVEDV FSITGRGTVA TGRIERGVVK VGEEVEIVGI 250
    HDVRKTVVTG IEMFRKLLDE GRSGDNVGAL LRGVDRTQIE RGQVLAKPGS 300
    IKPHTHYTSE VYVLTKEEGG RHTPFFDGYR PQFYFRTTDV TGVIKLPEGV 350
    EMVMPGDNVQ MEITLITPIA IEEGLRFAIR EGGRTVGSGV VAKMLAD 397
    Length:397
    Mass (Da):43,657
    Last modified:April 18, 2012 - v1
    Checksum:i0C26A872216D01C9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002987 Genomic DNA. Translation: AFA47707.1.
    CP002987 Genomic DNA. Translation: AFA49618.1.
    RefSeqiYP_005268596.1. NC_016894.1.
    YP_005270507.1. NC_016894.1.

    Genome annotation databases

    EnsemblBacteriaiAFA47707; AFA47707; Awo_c09160.
    AFA49618; AFA49618; Awo_c28670.
    GeneIDi11871367.
    11872836.
    KEGGiawo:Awo_c09160.
    awo:Awo_c28670.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002987 Genomic DNA. Translation: AFA47707.1 .
    CP002987 Genomic DNA. Translation: AFA49618.1 .
    RefSeqi YP_005268596.1. NC_016894.1.
    YP_005270507.1. NC_016894.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFA47707 ; AFA47707 ; Awo_c09160 .
    AFA49618 ; AFA49618 ; Awo_c28670 .
    GeneIDi 11871367.
    11872836.
    KEGGi awo:Awo_c09160.
    awo:Awo_c28670.

    Phylogenomic databases

    KOi K02358.
    OMAi RITISCE.

    Enzyme and pathway databases

    BioCyci AWOO931626:GI4Q-2865-MONOMER.
    AWOO931626:GI4Q-914-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complte genome sequence of Acetobacterium woodii."
      Poehlein A., Schmidt S., Kaster A.-K., Goenrich M., Vollmers J., Thuermer A., Gottschalk G., Thauer R.K., Daniel R., Mueller V.
      Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655Imported.
    2. "An ancient pathway combining carbon dioxide fixation with the generation and utilization of a sodium ion gradient for ATP synthesis."
      Poehlein A., Schmidt S., Kaster A.K., Goenrich M., Vollmers J., Thurmer A., Bertsch J., Schuchmann K., Voigt B., Hecker M., Daniel R., Thauer R.K., Gottschalk G., Muller V.
      PLoS ONE 7:E33439-E33439(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DSM 1030Imported.

    Entry informationi

    Entry nameiH6LGV4_ACEWD
    AccessioniPrimary (citable) accession number: H6LGV4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: April 18, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3