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Protein

Thymidine kinase

Gene

tdk

Organism
Saprospira grandis (strain Lewin)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSGRA984262:GLJW-3827-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkImported
Ordered Locus Names:SGRA_3788Imported
OrganismiSaprospira grandis (strain Lewin)Imported
Taxonomic identifieri984262 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesSphingobacteriiaSphingobacterialesSaprospiraceaeSaprospira
ProteomesiUP000007519 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

H6L8E0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGKLHLILG PMFSGKSTLL LTRYRRYRIA GKACLLVKYA KDCRYDDSAA
60 70 80 90 100
MIVTHDKLRY EATACTKLAE LDDLVQDYDV ICIDEIQFYP DAADFADRWA
110 120 130 140 150
NQGKIVECCG LSGDYKREPF EQISRLIPRC DDITHVKAVC KSSGLDAPFS
160 170 180
QRFSQEEEQE VIGGSDKYQA VSRAVYLQQQ KKED
Length:184
Mass (Da):20,952
Last modified:April 18, 2012 - v1
Checksum:i7E1C6D82DF5C0043
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002831 Genomic DNA. Translation: AFC26504.1.
RefSeqiWP_015694091.1. NC_016940.1.
YP_005324088.1. NC_016940.1.

Genome annotation databases

EnsemblBacteriaiAFC26504; AFC26504; SGRA_3788.
KEGGisgn:SGRA_3788.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002831 Genomic DNA. Translation: AFC26504.1.
RefSeqiWP_015694091.1. NC_016940.1.
YP_005324088.1. NC_016940.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFC26504; AFC26504; SGRA_3788.
KEGGisgn:SGRA_3788.

Enzyme and pathway databases

BioCyciSGRA984262:GLJW-3827-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequencing and analysis of Saprospira grandis str. Lewin, a predatory marine bacterium."
    Saw J., Yuryev A., Kanbe M., Hou S., Young A., Aizawa S., Alam M.
    Stand. Genomic Sci. 6:84-93(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LewinImported.

Entry informationi

Entry nameiH6L8E0_SAPGL
AccessioniPrimary (citable) accession number: H6L8E0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 1, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.