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Protein
Submitted name:

Hexokinase

Gene

TPEGAU_0505

Organism
Treponema pallidum subsp. pertenue (strain Gauthier)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. hexokinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciTPAL491080:GJ7X-540-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
HexokinaseImported (EC:2.7.1.1Imported)
Gene namesi
Ordered Locus Names:TPEGAU_0505Imported
OrganismiTreponema pallidum subsp. pertenue (strain Gauthier)Imported
Taxonomic identifieri491080 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000008192: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

H6KY26-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDQHTRTRDL VSAFFGRFHF DVQGPSVRTV VDVLRADMVR GLEEEAQLPP
60 70 80 90 100
RMGSALAMIP TWVAPPRVSP CNRRVIVIDA GGTNFRSCLV RFGDSGTPHI
110 120 130 140 150
ENLEKRPMPG TTREYSRTEF FGEIADNLAR LKGAADCIGF CFSYPIRIRP
160 170 180 190 200
DGDGEVIQFA KEIKAAEVIG TCVGAGLTEA LSARNWPELR SLKMLNDATS
210 220 230 240 250
ALLAGFFAAP EGCSFSSYVG FILGTGMNSA YLEPDPIPKI PAHHTPQVVV
260 270 280 290 300
CESGKSNKVP RSVFDELFTQ TTAEPDIAHL EKMSSGTYLG PLASVVVRLA
310 320 330 340 350
AQEGLFSHAV HAALSTVSFT LVDMDRFLFA PSVSTTTLGA LLAPGTDTDR
360 370 380 390 400
EILFLLLDAV VARAARIAAG VIAASVLKSG AGYDPLRPVC VLAEGTTFQC
410 420 430 440
TYRLRTRVTS HLQAFLTEER GVYFDIISLE NAVTLGSALG GLSS
Length:444
Mass (Da):47,792
Last modified:April 18, 2012 - v1
Checksum:i5ACC3E111491A43B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002376 Genomic DNA. Translation: AEZ59763.1.
RefSeqiWP_014342734.1. NC_016843.1.
YP_005222683.1. NC_016843.1.

Genome annotation databases

EnsemblBacteriaiAEZ59763; AEZ59763; TPEGAU_0505.
GeneIDi11852040.
KEGGitpg:TPEGAU_0505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002376 Genomic DNA. Translation: AEZ59763.1.
RefSeqiWP_014342734.1. NC_016843.1.
YP_005222683.1. NC_016843.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEZ59763; AEZ59763; TPEGAU_0505.
GeneIDi11852040.
KEGGitpg:TPEGAU_0505.

Phylogenomic databases

KOiK00844.

Enzyme and pathway databases

BioCyciTPAL491080:GJ7X-540-MONOMER.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence."
    Cejkova D., Zobanikova M., Chen L., Pospisilova P., Strouhal M., Qin X., Mikalova L., Norris S.J., Muzny D.M., Gibbs R.A., Fulton L.L., Sodergren E., Weinstock G.M., Smajs D.
    PLoS Negl. Trop. Dis. 6:E1471-E1471(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GauthierImported.

Entry informationi

Entry nameiH6KY26_TREPG
AccessioniPrimary (citable) accession number: H6KY26
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: January 7, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.