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Protein
Submitted name:

Prostasin

Gene

PRSS8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ProstasinImported
Gene namesi
Name:PRSS8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:9491. PRSS8.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000052344.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500841515430 – 107Sequence analysisAdd BLAST78

Proteomic databases

PeptideAtlasiH3BVC8.
PRIDEiH3BVC8.

Expressioni

Gene expression databases

BgeeiENSG00000052344.
ExpressionAtlasiH3BVC8. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 107Peptidase S1InterPro annotationAdd BLAST69

Sequence similaritiesi

Contains 1 peptidase S1 domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118810.

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H3BVC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKGVLGPG QLGAVAILLY LGLLRSGTAP CGVAPQARIT GGSSAVAGQW
60 70 80 90 100
PWQVSITYEG VHVCGGSLVS EQWVLSAAHC FPSEHHKEAY EVKLGAHQLD

SYSEDAK
Length:107
Mass (Da):11,188
Last modified:October 5, 2016 - v8
Checksum:iE4CF1C0A22CC2E16
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei107Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009088 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000567797; ENSP00000458056; ENSG00000052344.
UCSCiuc059tlp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009088 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH3BVC8.
PRIDEiH3BVC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000567797; ENSP00000458056; ENSG00000052344.
UCSCiuc059tlp.1. human.

Organism-specific databases

HGNCiHGNC:9491. PRSS8.
OpenTargetsiENSG00000052344.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118810.

Miscellaneous databases

ChiTaRSiPRSS8. human.

Gene expression databases

BgeeiENSG00000052344.
ExpressionAtlasiH3BVC8. baseline and differential.

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH3BVC8_HUMAN
AccessioniPrimary (citable) accession number: H3BVC8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: November 30, 2016
This is version 36 of the entry and version 8 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.