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Protein
Submitted name:

Transcription factor 4

Gene

TCF4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 4Imported
Gene namesi
Name:TCF4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000196628.13
HGNCiHGNC:11634 TCF4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196628

PTM / Processingi

Proteomic databases

MaxQBiH3BTP3
PeptideAtlasiH3BTP3
PRIDEiH3BTP3

Expressioni

Gene expression databases

BgeeiENSG00000196628
ExpressionAtlasiH3BTP3 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH3BTP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini574 – 627BHLHInterPro annotationAdd BLAST54

Phylogenomic databases

eggNOGiKOG3910 Eukaryota
ENOG410XYUA LUCA
GeneTreeiENSGT00510000046438

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

H3BTP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV
60 70 80 90 100
EDRSSSGSWG NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI
110 120 130 140 150
QSKTERGSYS SYGRESNLQG CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ
160 170 180 190 200
YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL PSSLVLSPQV YAPSASTADY
210 220 230 240 250
NRDSPGYPSS KPATSTFPSS FFMQDGHHSS DPWSSSSGMN QPGYAGMLGN
260 270 280 290 300
SSHIPQSSSY CSLHPHERLS YPSHSSADIN SSLPPMSTFH RSGTNHYSTS
310 320 330 340 350
SCTPPANGTD SIMANRGSGA AGSSQTGDAL GKALASIYSP DHTNNSFSSN
360 370 380 390 400
PSTPVGSPPS LSAGTAVWSR NGGQASSSPN YEGPLHSLQS RIEDRLERLD
410 420 430 440 450
DAIHVLRNHA VGPSTAMPGG HGDMHGIIGP SHNGAMGGLG SGYGTGLLSA
460 470 480 490 500
NRHSLMVGTH REDGVALRGS HSLLPNQVPV PQLPVQSATS PDLNPPQDPY
510 520 530 540 550
RGMPPGLQGQ SVSSGSSEIK SDDEGDENLQ DTKSSEDKKL DDDKKDIKSI
560 570 580 590 600
TRSRSSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM
610 620 630 640 650
VQLHLKSDKP QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK
660 670
VSSEPPPLSL AGPHPGMGDA SNHMGQM
Length:677
Mass (Da):72,432
Last modified:April 18, 2012 - v1
Checksum:iC2ED30EC6BF74EF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013587 Genomic DNA No translation available.
AC018994 Genomic DNA No translation available.
AC090383 Genomic DNA No translation available.
AC090684 Genomic DNA No translation available.
AC091103 Genomic DNA No translation available.
KF459816 Genomic DNA No translation available.
RefSeqiNP_001230157.1, NM_001243228.1
UniGeneiHs.605153
Hs.742885

Genome annotation databases

EnsembliENST00000564403; ENSP00000457263; ENSG00000196628
GeneIDi6925
UCSCiuc010dpi.4 human

Similar proteinsi

Entry informationi

Entry nameiH3BTP3_HUMAN
AccessioniPrimary (citable) accession number: H3BTP3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 25, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health