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Protein
Submitted name:

Guanine nucleotide-binding protein G(o) subunit alpha

Gene

GNAO1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerSAAS annotation
LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(o) subunit alphaImported
Gene namesi
Name:GNAO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000087258.13.
HGNCiHGNC:4389. GNAO1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087258.

PTM / Processingi

Proteomic databases

PaxDbiH3BTM2.
PeptideAtlasiH3BTM2.
PRIDEiH3BTM2.

Expressioni

Gene expression databases

BgeeiENSG00000087258.
ExpressionAtlasiH3BTM2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH3BTM2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0082. Eukaryota.
ENOG410XNVQ. LUCA.
GeneTreeiENSGT00760000118851.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
InterProiView protein in InterPro
IPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiView protein in Pfam
PF00503. G-alpha. 1 hit.
PRINTSiPR00318. GPROTEINA.
PR00441. GPROTEINAI.
SMARTiView protein in SMART
SM00275. G_alpha. 1 hit.
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

H3BTM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SRMEDTEPFS AELLSAMMRL WGDSGIQECF NRSREYQLND SAKYYLDSLD
60 70 80 90 100
RIGAADYQPT EQDILRTRVK TTGIVETHFT FKNLHFRLFD VGGQRSERKK
110 120 130 140 150
WIHCFEDVTA IIFCVALSGY DQVLHEDETT NRMHESLMLF DSICNNKFFI
160 170 180 190
DTSIILFLNK KDLFGEKIKK SPLTICFPEY TDCFTDSLLL TLISW
Length:195
Mass (Da):22,789
Last modified:June 7, 2017 - v2
Checksum:i8DD100B477220F21
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009102 Genomic DNA. No translation available.
AC079411 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000562316; ENSP00000457238; ENSG00000087258.
UCSCiuc059ujq.1. human.

Similar proteinsi

Entry informationi

Entry nameiH3BTM2_HUMAN
AccessioniPrimary (citable) accession number: H3BTM2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: June 7, 2017
Last modified: September 27, 2017
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported