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Protein
Submitted name:

Guanine nucleotide-binding protein G(o) subunit alpha

Gene

GNAO1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerSAAS annotation
LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(o) subunit alphaImported
Gene namesi
Name:GNAO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000087258.13
HGNCiHGNC:4389 GNAO1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087258

PTM / Processingi

Proteomic databases

EPDiH3BTM2
PeptideAtlasiH3BTM2
PRIDEiH3BTM2

Expressioni

Gene expression databases

BgeeiENSG00000087258
ExpressionAtlasiH3BTM2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BTM2
SMRiH3BTM2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0082 Eukaryota
ENOG410XNVQ LUCA
GeneTreeiENSGT00760000118851

Family and domain databases

CDDicd00066 G-alpha, 1 hit
InterProiView protein in InterPro
IPR001408 Gprotein_alpha_I
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase
PANTHERiPTHR10218 PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503 G-alpha, 1 hit
PRINTSiPR00318 GPROTEINA
PR00441 GPROTEINAI
SMARTiView protein in SMART
SM00275 G_alpha, 1 hit
SUPFAMiSSF47895 SSF47895, 1 hit
SSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Fragment.

H3BTM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SRMEDTEPFS AELLSAMMRL WGDSGIQECF NRSREYQLND SAKYYLDSLD
60 70 80 90 100
RIGAADYQPT EQDILRTRVK TTGIVETHFT FKNLHFRLFD VGGQRSERKK
110 120 130 140 150
WIHCFEDVTA IIFCVALSGY DQVLHEDETT NRMHESLMLF DSICNNKFFI
160 170 180 190
DTSIILFLNK KDLFGEKIKK SPLTICFPEY TDCFTDSLLL TLISW
Length:195
Mass (Da):22,789
Last modified:June 7, 2017 - v2
Checksum:i8DD100B477220F21
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009102 Genomic DNA No translation available.
AC079411 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000562316; ENSP00000457238; ENSG00000087258
UCSCiuc059ujq.1 human

Similar proteinsi

Entry informationi

Entry nameiH3BTM2_HUMAN
AccessioniPrimary (citable) accession number: H3BTM2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: June 7, 2017
Last modified: March 28, 2018
This is version 49 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported