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Protein
Submitted name:

Mannose-6-phosphate isomerase

Gene

MPI

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mannose-6-phosphate isomeraseImported
Gene namesi
Name:MPIImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000178802.17.
HGNCiHGNC:7216. MPI.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000178802.

PTM / Processingi

Proteomic databases

MaxQBiH3BT48.
PaxDbiH3BT48.
PeptideAtlasiH3BT48.
PRIDEiH3BT48.

Expressioni

Gene expression databases

BgeeiENSG00000178802.
ExpressionAtlasiH3BT48. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH3BT48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannose-6-phosphate isomerase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2757. Eukaryota.
COG1482. LUCA.
GeneTreeiENSGT00390000016075.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiView protein in InterPro
IPR001250. Man6P_Isoase-1.
IPR016305. Mannose-6-P_Isomerase.
IPR018050. Pmannose_isomerase-type1_CS.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin_sf.
PANTHERiPTHR10309. PTHR10309. 1 hit.
PfamiView protein in Pfam
PF01238. PMI_typeI. 1 hit.
PRINTSiPR00714. MAN6PISMRASE.
SUPFAMiSSF51182. SSF51182. 1 hit.
TIGRFAMsiTIGR00218. manA. 1 hit.
PROSITEiView protein in PROSITE
PS00965. PMI_I_1. 1 hit.

Sequencei

Sequence statusi: Complete.

H3BT48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK ILDNRISQKT
60 70 80 90 100
LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK
110 120 130 140 150
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL
160 170 180 190 200
IGDEAATHLK QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI
210 220 230 240 250
SQQAAAGNNM EDIFGELLLQ LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL
260 270 280 290 300
EANVPHAYLK GGEPHFSSEP HCHPCWALFP YLDKGRRRVV KETPKDLAAL
310
TSEGSWAQQA TAGRDDECI
Length:319
Mass (Da):35,484
Last modified:April 18, 2012 - v1
Checksum:iBD36F747F924E5E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125435 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000562606; ENSP00000457020; ENSG00000178802.
UCSCiuc059lnh.1. human.

Similar proteinsi

Entry informationi

Entry nameiH3BT48_HUMAN
AccessioniPrimary (citable) accession number: H3BT48
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 22, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported