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Protein
Submitted name:

Guanine nucleotide-binding protein G(o) subunit alpha

Gene

GNAO1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(o) subunit alphaImported
Gene namesi
Name:GNAO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:4389. GNAO1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087258.

PTM / Processingi

Proteomic databases

PaxDbiH3BNR5.
PeptideAtlasiH3BNR5.
PRIDEiH3BNR5.

Expressioni

Gene expression databases

BgeeiENSG00000087258.
ExpressionAtlasiH3BNR5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262493.

Structurei

3D structure databases

ProteinModelPortaliH3BNR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0082. Eukaryota.
ENOG410XNVQ. LUCA.
GeneTreeiENSGT00760000118851.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00441. GPROTEINAI.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

H3BNR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IDTSIILFLN KKDLFGEKIK KSPLTICFPE YTGPNTYEDA AAYIQAQFES
60 70 80 90
KNRSPNKEIY CHMTCATDTN NIQVVFDAVT DIIIANNLRG CGLY
Length:94
Mass (Da):10,586
Last modified:April 18, 2012 - v1
Checksum:i6EF376653DC1988E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009102 Genomic DNA. No translation available.
AC079411 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000564727; ENSP00000454971; ENSG00000087258.
UCSCiuc059ujw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009102 Genomic DNA. No translation available.
AC079411 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliH3BNR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262493.

Proteomic databases

PaxDbiH3BNR5.
PeptideAtlasiH3BNR5.
PRIDEiH3BNR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000564727; ENSP00000454971; ENSG00000087258.
UCSCiuc059ujw.1. human.

Organism-specific databases

HGNCiHGNC:4389. GNAO1.
OpenTargetsiENSG00000087258.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0082. Eukaryota.
ENOG410XNVQ. LUCA.
GeneTreeiENSGT00760000118851.

Miscellaneous databases

ChiTaRSiGNAO1. human.

Gene expression databases

BgeeiENSG00000087258.
ExpressionAtlasiH3BNR5. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00441. GPROTEINAI.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiH3BNR5_HUMAN
AccessioniPrimary (citable) accession number: H3BNR5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 30, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.