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Protein

Transporter

Gene

SLC6A2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:SLC6A2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000103546.18.
HGNCiHGNC:11048. SLC6A2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 83HelicalSequence analysisAdd BLAST19
Transmembranei95 – 116HelicalSequence analysisAdd BLAST22
Transmembranei137 – 164HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103546.

PTM / Processingi

Proteomic databases

MaxQBiH3BMY5.
PaxDbiH3BMY5.
PeptideAtlasiH3BMY5.
PRIDEiH3BMY5.

Expressioni

Gene expression databases

BgeeiENSG00000103546.
ExpressionAtlasiH3BMY5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH3BMY5.
SMRiH3BMY5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3659. Eukaryota.
COG0733. LUCA.
GeneTreeiENSGT00760000118857.

Family and domain databases

InterProiView protein in InterPro
IPR000175. Na/ntran_symport.
IPR037272. SNS_sf.
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiView protein in Pfam
PF00209. SNF. 1 hit.
PRINTSiPR00176. NANEUSMPORT.
SUPFAMiSSF161070. SSF161070. 1 hit.
PROSITEiView protein in PROSITE
PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

H3BMY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLARMNPQV QPENNGADTG PEQPLRARKT AELLVVKERN GVQCLLAPRD
60 70 80 90 100
GDAQPRETWG KKIDFLLSVV GFAVDLANVW RFPYLCYKNG GGAFLIPYTL
110 120 130 140 150
FLIIAGMPLF YMELALGQYN REGAATVWKI CPFFKGVGYA VILIALYVGF
160 170 180 190 200
YYNVIIAWSL YYLFSSFTLN LPWTDCGHTW NSPNCTDPKL LNGSVLGNHT
Length:200
Mass (Da):22,409
Last modified:April 18, 2012 - v1
Checksum:iD7667727D99D2A6A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei200Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136621 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000568655; ENSP00000454603; ENSG00000103546.
UCSCiuc059uio.1. human.

Similar proteinsi

Entry informationi

Entry nameiH3BMY5_HUMAN
AccessioniPrimary (citable) accession number: H3BMY5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 22, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported