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Protein
Submitted name:

NEDD8 ultimate buster 1

Gene

NUB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NEDD8 ultimate buster 1Imported
Submitted name:
NEDD8 ultimate buster-1, isoform CRA_dImported
Gene namesi
Name:NUB1Imported
Synonyms:NYREN18Imported
ORF Names:hCG_19587Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:17623. NUB1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiH3BM14.
PaxDbiH3BM14.

Expressioni

Gene expression databases

ExpressionAtlasiH3BM14. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000457628.

Structurei

3D structure databases

ProteinModelPortaliH3BM14.
SMRiH3BM14. Positions 95-185, 480-554.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini398 – 43841UBAInterPro annotationAdd
BLAST
Domaini499 – 53941UBAInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili435 – 46026Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2561. Eukaryota.
ENOG410ZK3P. LUCA.
GeneTreeiENSGT00390000010557.
OrthoDBiEOG7Z69CD.

Family and domain databases

InterProiIPR011990. TPR-like_helical_dom.
IPR015940. UBA.
IPR009060. UBA-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00627. UBA. 2 hits.
[Graphical view]
SMARTiSM00165. UBA. 2 hits.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 2 hits.
SSF48452. SSF48452. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50030. UBA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H3BM14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTNGGRCRI RALCWSRREW RGAGMAQKKY LQAKLTQFLR EDRIQLWKPP
60 70 80 90 100
YTDENKKVGL ALKDLAKQYS DRLECCENEV EKVIEEIRCK AIERGTGNDN
110 120 130 140 150
YRTTGIATIE VFLPPRLKKD RKNLLETRLH ITGRELRSKI AETFGLQENY
160 170 180 190 200
IKIVINKKQL QLGKTLEEQG VAHNVKAMVL ELKQSEEDAR KNFQLEEEEQ
210 220 230 240 250
NEAKLKEKQI QRTKRGLEIL AKRAAETVVD PEMTPYLDIA NQTGRSIRIP
260 270 280 290 300
PSERKALMLA MGYHEKGRAF LKRKEYGIAL PCLLDADKYF CECCRELLDT
310 320 330 340 350
VDNYAVLQLD IVWCYFRLEQ LECLDDAEKK LNLAQKCFKN CYGENHQRLV
360 370 380 390 400
HIKGNCGKEK VLFLRLYLLQ GIRNYHSGND VEAYEYLNKA RQLFKELYID
410 420 430 440 450
PSKVDNLLQL GFTAQEARLG LRACDGNVDH AATHITNRRE ELAQIRKEEK
460 470 480 490 500
EKKRRRLENI RFLKGMGYST HAAQQILLSN PQMWWLNDSN PETDNRQESP
510 520 530 540 550
SQENIDRLVY MGFDALVAEA ALRVFRGNVQ LAAQTLAHNG GSLPPELPLS
560 570 580 590 600
PEDSLSPPAT SPSDSAGTSS ASTDEDMETE AVNEILEDIP EHEEDYLDST
610 620
LEDEEIIIAE YLSYVENRKS ATKKN
Length:625
Mass (Da):71,922
Last modified:April 18, 2012 - v1
Checksum:i3FCE0F9C0C881300
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005486 Genomic DNA. No translation available.
KF458635 Genomic DNA. No translation available.
KF458638 Genomic DNA. No translation available.
CH471173 Genomic DNA. Translation: EAW54003.1.
RefSeqiNP_057202.3. NM_016118.4.
UniGeneiHs.647082.

Genome annotation databases

EnsembliENST00000413040; ENSP00000398644; ENSG00000013374.
GeneIDi51667.
UCSCiuc003wjw.6. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005486 Genomic DNA. No translation available.
KF458635 Genomic DNA. No translation available.
KF458638 Genomic DNA. No translation available.
CH471173 Genomic DNA. Translation: EAW54003.1.
RefSeqiNP_057202.3. NM_016118.4.
UniGeneiHs.647082.

3D structure databases

ProteinModelPortaliH3BM14.
SMRiH3BM14. Positions 95-185, 480-554.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000457628.

Proteomic databases

EPDiH3BM14.
PaxDbiH3BM14.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413040; ENSP00000398644; ENSG00000013374.
GeneIDi51667.
UCSCiuc003wjw.6. human.

Organism-specific databases

CTDi51667.
HGNCiHGNC:17623. NUB1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2561. Eukaryota.
ENOG410ZK3P. LUCA.
GeneTreeiENSGT00390000010557.
OrthoDBiEOG7Z69CD.

Miscellaneous databases

ChiTaRSiNUB1. human.
GenomeRNAii51667.

Gene expression databases

ExpressionAtlasiH3BM14. baseline and differential.

Family and domain databases

InterProiIPR011990. TPR-like_helical_dom.
IPR015940. UBA.
IPR009060. UBA-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00627. UBA. 2 hits.
[Graphical view]
SMARTiSM00165. UBA. 2 hits.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 2 hits.
SSF48452. SSF48452. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50030. UBA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiH3BM14_HUMAN
AccessioniPrimary (citable) accession number: H3BM14
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: June 8, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.