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Protein
Submitted name:

Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, isoform CRA_a

Gene

Tirap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Enzyme and pathway databases

ReactomeiR-MMU-166058 MyD88:Mal cascade initiated on plasma membrane

Names & Taxonomyi

Protein namesi
Submitted name:
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, isoform CRA_aImported
Submitted name:
Toll/interleukin-1 receptor domain-containing adapter proteinImported
Gene namesi
Name:TirapImported
ORF Names:mCG_7460Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2152213 Tirap

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000032041

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 196TIRInterPro annotationAdd BLAST85

Phylogenomic databases

eggNOGiENOG410IVIY Eukaryota
ENOG411205V LUCA
GeneTreeiENSGT00510000048428
KOiK05403
OMAiDVCVCHS
OrthoDBiEOG091G0EQB
TreeFamiTF330734

Family and domain databases

Gene3Di3.40.50.10140, 1 hit
InterProiView protein in InterPro
IPR000157 TIR_dom
IPR017279 Tol-interleuk_rcpt_adapt_Tirap
IPR035897 Toll_tir_struct_dom_sf
PANTHERiPTHR22662 PTHR22662, 1 hit
PfamiView protein in Pfam
PF13676 TIR_2, 1 hit
PIRSFiPIRSF037750 TIR_Tirap, 1 hit
SUPFAMiSSF52200 SSF52200, 1 hit
PROSITEiView protein in PROSITE
PS50104 TIR, 1 hit

Sequencei

Sequence statusi: Complete.

H3BKL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSLEACTMA SSSSVPASST PSKKPRDKIA DWFRQALLKK PKKMPISQES
60 70 80 90 100
HLYDGSQTAT QDGLSPSSCS SPPSHSSPES RSSPSSCSSG MSPTSPPTHV
110 120 130 140 150
DSSSSSSGRW SKDYDVCVCH SEEDLEAAQE LVSYLEGSQA SLRCFLQLRD
160 170 180 190 200
AAPGGAIVSE LCQALSRSHC RVLLITPGFL RDPWCKYQML QALTEAPASE
210 220 230 240
GCTIPLLSGL SRAAYPPELR FMYYVDGRGK DGGFYQVKEA VIHYLETLS
Length:249
Mass (Da):26,898
Last modified:April 18, 2012 - v1
Checksum:i3951244F9C07CD14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140448 Genomic DNA No translation available.
CH466522 Genomic DNA Translation: EDL25378.1
CH466522 Genomic DNA Translation: EDL25380.1
RefSeqiNP_001171316.1, NM_001177845.1
NP_001171317.1, NM_001177846.1
NP_001171318.1, NM_001177847.1
NP_473437.2, NM_054096.2
UniGeneiMm.23987

Genome annotation databases

EnsembliENSMUST00000175765; ENSMUSP00000135435; ENSMUSG00000032041
ENSMUST00000176531; ENSMUSP00000135224; ENSMUSG00000032041
ENSMUST00000176685; ENSMUSP00000135876; ENSMUSG00000032041
ENSMUST00000177129; ENSMUSP00000135462; ENSMUSG00000032041
GeneIDi117149
KEGGimmu:117149
UCSCiuc009osq.2 mouse

Similar proteinsi

Entry informationi

Entry nameiH3BKL1_MOUSE
AccessioniPrimary (citable) accession number: H3BKL1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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