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Protein
Submitted name:

Myotubularin-related protein 5

Gene

Sbf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • pseudophosphatase activity Source: MGI
  • Rab guanyl-nucleotide exchange factor activity Source: MGI

GO - Biological processi

  • negative regulation of catalytic activity Source: GOC
  • positive regulation of GTPase activity Source: MGI
  • regulation of cell growth Source: MGI
  • spermatogenesis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Myotubularin-related protein 5Imported
Gene namesi
Name:Sbf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1925230. Sbf1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000118107.

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains myotubularin phosphatase domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118832.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR030574. MTMR5.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH-like_dom.
IPR001849. PH_domain.
IPR029021. Prot-tyrosine_phosphatase-like.
[Graphical view]
PANTHERiPTHR10807. PTHR10807. 1 hit.
PTHR10807:SF43. PTHR10807:SF43. 1 hit.
PfamiPF06602. Myotub-related. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS51339. PPASE_MYOTUBULARIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H3BKD9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XFYRTLEGFR LLVEKEWLSF GHRFSHRGAH TLAGQSSGFT PVFLQFLDCV
60 70 80 90 100
HQVHLQFPME FEFSQFYLKF LGYHHTSRRF RTFLLDSDYE RIELGLLYEE
110 120 130 140 150
KGERRGQLAC KSVWEYVDRL SKRTPMFYNY TYAPEDTEVW DFYTEETLAE
160 170 180 190 200
GPPYDWELAQ GPPEPPEEER PDGGAPQSRR RVVWPCYDSR PRVQPDAISR
210 220 230 240 250
LLEELQRLET ELGRPSERWK DTWDRVKAAQ RLESRQDGRG TPSSLLVSAV
260 270 280 290 300
PHHRRSLGVY LQEGPVGSTL SLSLDSDQSS GSTTSSSRQA ARRSTSTLYS
310 320 330 340 350
QFQTAESENR SYEGILYKKG AFMKPWKARW FVLDKTKHQL RYYDHRMDTE
360 370 380 390 400
CKGVIDLAEV EAVAPGTPTI GAPKTVDEKA FFDVKTTRRV YNFCAQDVPS
410
AQQWVDRIQS CLSDA
Length:415
Mass (Da):48,123
Last modified:April 18, 2012 - v1
Checksum:i254576AE3E57F11C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160538 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000175778; ENSMUSP00000135351; ENSMUSG00000036529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160538 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000118107.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000175778; ENSMUSP00000135351; ENSMUSG00000036529.

Organism-specific databases

MGIiMGI:1925230. Sbf1.

Phylogenomic databases

GeneTreeiENSGT00760000118832.

Miscellaneous databases

ChiTaRSiSbf1. mouse.
NextBioi35561790.
SOURCEiSearch...

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR030574. MTMR5.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH-like_dom.
IPR001849. PH_domain.
IPR029021. Prot-tyrosine_phosphatase-like.
[Graphical view]
PANTHERiPTHR10807. PTHR10807. 1 hit.
PTHR10807:SF43. PTHR10807:SF43. 1 hit.
PfamiPF06602. Myotub-related. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS51339. PPASE_MYOTUBULARIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH3BKD9_MOUSE
AccessioniPrimary (citable) accession number: H3BKD9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: July 22, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.