H3BK41 (H3BK41_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Neurexin-1 Ensembl ENSMUSP00000135241

Gene names

Name:

Nrxn1 Ensembl ENSMUSP00000135241 MGI 1096391

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000135241

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	214 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000135241

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS001791 Repeat SAAS SAAS001791
PTM	Disulfide bond SAAS SAAS001791
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	neurotransmitter secretion Inferred from genetic interaction PubMed 12827191. Source: MGI positive regulation of synapse assembly Inferred from genetic interaction PubMed 21356198. Source: MGI positive regulation of synapse maturation Inferred from direct assay PubMed 19567877. Source: MGI synapse assembly Inferred from genetic interaction PubMed 12827191. Source: MGI
Cellular_component	presynaptic membrane Inferred from direct assay PubMed 12827191. Source: MGI
Molecular_function	acetylcholine receptor binding Inferred from direct assay PubMed 19567877. Source: MGI calcium channel regulator activity Inferred from genetic interaction PubMed 12827191. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSMUSP00000135241
	Non-terminal residue	214	1	Ensembl ENSMUSP00000135241

Sequences

	Sequence		Length	Mass (Da)
	H3BK41 [UniParc]. Last modified April 18, 2012. Version 1. Checksum: 5D6183E077CA5724	FASTA	214	23,110
	10 20 30 40 50 60 DLGNGANLIK GSSNKPLNDN QWHNVMISRD TSNLHTVKID TKITTQITAG ARNLDLKSDL 70 80 90 100 110 120 YIGGVAKETY KSLPKLVHAK EGFQGCLASV DLNGRLPDLI SDALFCNGQI ERGCEVALMK 130 140 150 160 170 180 ADLQGPSTTC QEDSCSNQGV CLQQWDGFSC DCSMTSFSGP LCNDPGTTYI FSKGGGQITY 190 200 210 KWPPNDRPST RADRLAIGFS TVQKEAVLVR VDSS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000135241.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000135241.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC101872 Genomic DNA. No translation available. AC131326 Genomic DNA. No translation available. AC151286 Genomic DNA. No translation available. AC154325 Genomic DNA. No translation available. AC154599 Genomic DNA. No translation available. AC167814 Genomic DNA. No translation available. AC170901 Genomic DNA. No translation available. AC171209 Genomic DNA. No translation available. CT025708 Genomic DNA. No translation available. CT486002 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000176118; ENSMUSP00000135241; ENSMUSG00000024109.
Organism-specific databases
MGI	MGI:1096391. Nrxn1.
Phylogenomic databases
GeneTree	ENSGT00560000076996.
Gene expression databases
ArrayExpress	H3BK41.
Bgee	H3BK41.
Family and domain databases
Gene3D	2.60.120.200. 2 hits.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR000742. EG-like_dom. IPR001791. Laminin_G. IPR027158. NRXN1-alpha. [Graphical view]
PANTHER	PTHR10127:SF309. PTHR10127:SF309. 1 hit.
Pfam	PF00008. EGF. 1 hit. PF02210. Laminin_G_2. 1 hit. [Graphical view]
SMART	SM00181. EGF. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 2 hits.
PROSITE	PS50026. EGF_3. 1 hit. PS50025. LAM_G_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NRXN1. mouse.
NextBio	35561707.
SOURCE	Search...

Entry information

Entry name

H3BK41_MOUSE

Accession

Primary (citable) accession number: H3BK41

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2012
Last sequence update:	April 18, 2012
Last modified:	May 29, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)