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H3BK41

- H3BK41_MOUSE

UniProt

H3BK41 - H3BK41_MOUSE

Protein
Submitted name:

Neurexin-1

Gene

Nrxn1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 2 (14 May 2014)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. acetylcholine receptor binding Source: MGI
    2. calcium channel regulator activity Source: MGI
    3. protein binding Source: MGI

    GO - Biological processi

    1. neurotransmitter secretion Source: MGI
    2. positive regulation of synapse assembly Source: MGI
    3. positive regulation of synapse maturation Source: MGI
    4. regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
    5. synapse assembly Source: MGI
    6. synaptic transmission Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Neurexin-1Imported
    Gene namesi
    Name:Nrxn1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1096391. Nrxn1.

    Subcellular locationi

    GO - Cellular componenti

    1. presynaptic membrane Source: MGI

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    BgeeiH3BK41.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117263.

    Family and domain databases

    Gene3Di2.60.120.200. 2 hits.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000742. EG-like_dom.
    IPR001791. Laminin_G.
    [Graphical view]
    PfamiPF00008. EGF. 1 hit.
    PF02210. Laminin_G_2. 1 hit.
    [Graphical view]
    SMARTiSM00181. EGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 2 hits.
    PROSITEiPS50026. EGF_3. 1 hit.
    PS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    H3BK41-1 [UniParc]FASTAAdd to Basket

    « Hide

    DLGNGANLIK GSSNKPLNDN QWHNVMISRD TSNLHTVKID TKITTQITAG    50
    ARNLDLKSDL YIGGVAKETY KSLPKLVHAK EGFQGCLASV DLNGRLPDLI 100
    SDALFCNGQI ERGCEVALMK ADLQGPSTTC QEDSCSNQGV CLQQWDGFSC 150
    DCSMTSFSGP LCNDPGTTYI FSKGGGQITY KWPPNDRPST RADRLAIGFS 200
    TVQKEAVLVR VDS 213
    Length:213
    Mass (Da):23,023
    Last modified:May 14, 2014 - v2
    Checksum:i1183E077CA572436
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei213 – 2131Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC101872 Genomic DNA. No translation available.
    AC131326 Genomic DNA. No translation available.
    AC151286 Genomic DNA. No translation available.
    AC154325 Genomic DNA. No translation available.
    AC154599 Genomic DNA. No translation available.
    AC167814 Genomic DNA. No translation available.
    AC170901 Genomic DNA. No translation available.
    AC171209 Genomic DNA. No translation available.
    CT025708 Genomic DNA. No translation available.
    CT486002 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000176118; ENSMUSP00000135241; ENSMUSG00000024109.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC101872 Genomic DNA. No translation available.
    AC131326 Genomic DNA. No translation available.
    AC151286 Genomic DNA. No translation available.
    AC154325 Genomic DNA. No translation available.
    AC154599 Genomic DNA. No translation available.
    AC167814 Genomic DNA. No translation available.
    AC170901 Genomic DNA. No translation available.
    AC171209 Genomic DNA. No translation available.
    CT025708 Genomic DNA. No translation available.
    CT486002 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000176118 ; ENSMUSP00000135241 ; ENSMUSG00000024109 .

    Organism-specific databases

    MGIi MGI:1096391. Nrxn1.

    Phylogenomic databases

    GeneTreei ENSGT00750000117263.

    Miscellaneous databases

    ChiTaRSi NRXN1. mouse.
    NextBioi 35561707.
    SOURCEi Search...

    Gene expression databases

    Bgeei H3BK41.

    Family and domain databases

    Gene3Di 2.60.120.200. 2 hits.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000742. EG-like_dom.
    IPR001791. Laminin_G.
    [Graphical view ]
    Pfami PF00008. EGF. 1 hit.
    PF02210. Laminin_G_2. 1 hit.
    [Graphical view ]
    SMARTi SM00181. EGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 2 hits.
    PROSITEi PS50026. EGF_3. 1 hit.
    PS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiH3BK41_MOUSE
    AccessioniPrimary (citable) accession number: H3BK41
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2012
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 21 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3