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Protein
Submitted name:

Neurexin-1

Gene

Nrxn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. acetylcholine receptor binding Source: MGI
  2. calcium channel regulator activity Source: MGI

GO - Biological processi

  1. adult behavior Source: MGI
  2. learning Source: MGI
  3. neurotransmitter secretion Source: MGI
  4. positive regulation of synapse assembly Source: MGI
  5. positive regulation of synapse maturation Source: MGI
  6. regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
  7. social behavior Source: MGI
  8. synapse assembly Source: MGI
  9. synaptic transmission Source: MGI
  10. vesicle docking involved in exocytosis Source: MGI
  11. vocalization behavior Source: MGI
  12. vocal learning Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neurexin-1Imported
Gene namesi
Name:Nrxn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1096391. Nrxn1.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: MGI
  2. plasma membrane Source: MGI
  3. presynaptic membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiH3BK41.
ExpressionAtlasiH3BK41. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Family and domain databases

Gene3Di2.60.120.200. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 1 hit.
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

H3BK41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DLGNGANLIK GSSNKPLNDN QWHNVMISRD TSNLHTVKID TKITTQITAG
60 70 80 90 100
ARNLDLKSDL YIGGVAKETY KSLPKLVHAK EGFQGCLASV DLNGRLPDLI
110 120 130 140 150
SDALFCNGQI ERGCEVALMK ADLQGPSTTC QEDSCSNQGV CLQQWDGFSC
160 170 180 190 200
DCSMTSFSGP LCNDPGTTYI FSKGGGQITY KWPPNDRPST RADRLAIGFS
210
TVQKEAVLVR VDS
Length:213
Mass (Da):23,023
Last modified:February 4, 2015 - v4
Checksum:i1183E077CA572436
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei213 – 2131Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000176118; ENSMUSP00000135241; ENSMUSG00000024109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000176118; ENSMUSP00000135241; ENSMUSG00000024109.

Organism-specific databases

MGIiMGI:1096391. Nrxn1.

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Miscellaneous databases

ChiTaRSiNrxn1. mouse.
NextBioi35561707.
SOURCEiSearch...

Gene expression databases

BgeeiH3BK41.
ExpressionAtlasiH3BK41. baseline and differential.

Family and domain databases

Gene3Di2.60.120.200. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 1 hit.
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH3BK41_MOUSE
AccessioniPrimary (citable) accession number: H3BK41
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: February 4, 2015
Last modified: February 4, 2015
This is version 25 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.