Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Homeobox protein cut-like

Gene

Cux1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-6811438. Intra-Golgi traffic.

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein cut-likeUniRule annotation
Gene namesi
Name:Cux1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:88568. Cux1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiH3BK24.

Expressioni

Gene expression databases

BgeeiH3BK24.
ExpressionAtlasiH3BK24. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH3BK24.
SMRiH3BK24. Positions 556-638, 918-1008, 1100-1188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini551 – 63888CUT DNA-bindingInterPro annotationAdd
BLAST
Domaini918 – 100588CUT DNA-bindingInterPro annotationAdd
BLAST
Domaini1101 – 118888CUT DNA-bindingInterPro annotationAdd
BLAST
Domaini1226 – 128661Homeobox DNA-bindingInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili112 – 19685Sequence analysisAdd
BLAST
Coiled coili201 – 22828Sequence analysisAdd
BLAST
Coiled coili237 – 27438Sequence analysisAdd
BLAST
Coiled coili294 – 35360Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation
Contains 3 CUT DNA-binding domains.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000063019.
KOiK09313.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 3 hits.
InterProiIPR003350. CUT_dom.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02376. CUT. 3 hits.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM01109. CUT. 3 hits.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 3 hits.
PROSITEiPS51042. CUT. 3 hits.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H3BK24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR
60 70 80 90 100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP
110 120 130 140 150
DPVPALDVGQ QLEIKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKSQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK
210 220 230 240 250
LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA
260 270 280 290 300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVAIE VLTRSSLEVE
310 320 330 340 350
LAAKEREIAQ LVEDVQRLQA SLTKLRENSA SQISQLEQQL NAKNSTLKQL
360 370 380 390 400
EEKLKGQADY EEVKKELNTL KSMEFAPSEG AGTQDSTKPL EVLLLEKNRS
410 420 430 440 450
LQSENATLRI SNSDLSGSAR RKGRDQPESR RPGPLPASPP PQLPRNTGEQ
460 470 480 490 500
VSNTNGTHHF SPAGLSQDFF SSNLASPSLP LASTGKFALN SLLQRQLMQS
510 520 530 540 550
FYSKAMQEAG STSTIFSTGP YSTNSISSPS PLQQSPDVNG MAPSPSQSES
560 570 580 590 600
AGSISEGEEI DTAEIARQVK EQLIKHNIGQ RIFGHYVLGL SQGSVSEILA
610 620 630 640 650
RPKPWNKLTV RGKEPFHKMK QFLSDEQNIL ALRSIQGRQR GNITTRIRAS
660 670 680 690 700
ETGSDEAIKS ILEQAKRELQ VQKTAEPVQT SSTSSSGNSD DAIRSILQQA
710 720 730 740 750
RREMEAQQAA LDPALKPAPL SQPDLTILTP KHLSASPMST VSTYPPLAIS
760 770 780 790 800
LKKTPAAPET STAALPSAPA LKKEAQDVPT LDPPGSADAA QGVLRPMKSE
810 820 830 840 850
LVRGSTWKDP WWSPIQPERR NLTSSEETKA DETTASGKER AGSSQPRAER
860 870 880 890 900
SQLQGPSASA EYWKEWPSAE SPYSQSSELS LTGASRSETP QNSPLPSSPI
910 920 930 940 950
VPMAKPAKPS VPPLTPEQYE VYMYQEVDTI ELTRQVKEKL AKNGICQRIF
960 970 980 990 1000
GEKVLGLSQG SVSDMLSRPK PWSKLTQKGR EPFIRMQLWL NGELGQGVLP
1010 1020 1030 1040 1050
VQGQQQGPVL HSVASLQDPL QQGCVSSEST PKTSASCSPA PESPMSSSES
1060 1070 1080 1090 1100
VKSLTELVQQ PCPAIETSKE GKPPEPSDPP ASDSQPTTPL PLSGHSALSI
1110 1120 1130 1140 1150
QELVAMSPEL DTYGITKRVK EVLTDNNLGQ RLFGETILGL TQGSVSDLLA
1160 1170 1180 1190 1200
RPKPWHKLSL KGREPFVRMQ LWLNDPNNVE KLMDMKRMEK KAYMKRRHSS
1210 1220 1230 1240 1250
VSDSQPCEPP SVGIDYSQGA SPQPQHQLKK PRVVLAPEEK EALKRAYQQK
1260 1270 1280 1290 1300
PYPSPKTIEE LATQLNLKTS TVINWFHNYR SRIRRELFIE EIQAGSQGQA
1310 1320 1330 1340 1350
GASDSPSARS SRAAPSSEGD SCDGVEATDA EEPGGNIVAT KSQGGLAEVA
1360 1370 1380 1390 1400
AAPADREEAT QPAEKAKAQP LCSGTPGQDD GEDASRPRPL PEGLADAPAP
1410 1420 1430 1440 1450
VPSLAAPAAG EDAATSATAP ATATEAPGAA RAGPAERSSA LPSTSAPANA
1460 1470 1480 1490 1500
PARRPSSLQS LFGLPEAAGA RDNLVRKKKA ANLNSIIHRL EKAASREEPI

EWEF
Length:1,504
Mass (Da):164,503
Last modified:February 19, 2014 - v2
Checksum:iFF5EEBFC0FA75946
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC080158 Genomic DNA. No translation available.
AC083890 Genomic DNA. No translation available.
AC087329 Genomic DNA. No translation available.
RefSeqiNP_001278163.1. NM_001291234.1.
UniGeneiMm.320317.
Mm.436792.

Genome annotation databases

EnsembliENSMUST00000175975; ENSMUSP00000135223; ENSMUSG00000029705.
GeneIDi13047.
KEGGimmu:13047.
UCSCiuc009aas.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC080158 Genomic DNA. No translation available.
AC083890 Genomic DNA. No translation available.
AC087329 Genomic DNA. No translation available.
RefSeqiNP_001278163.1. NM_001291234.1.
UniGeneiMm.320317.
Mm.436792.

3D structure databases

ProteinModelPortaliH3BK24.
SMRiH3BK24. Positions 556-638, 918-1008, 1100-1188.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH3BK24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000175975; ENSMUSP00000135223; ENSMUSG00000029705.
GeneIDi13047.
KEGGimmu:13047.
UCSCiuc009aas.2. mouse.

Organism-specific databases

CTDi1523.
MGIiMGI:88568. Cux1.

Phylogenomic databases

GeneTreeiENSGT00530000063019.
KOiK09313.

Enzyme and pathway databases

ReactomeiR-MMU-6811438. Intra-Golgi traffic.

Miscellaneous databases

ChiTaRSiCux1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiH3BK24.
ExpressionAtlasiH3BK24. baseline and differential.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 3 hits.
InterProiIPR003350. CUT_dom.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02376. CUT. 3 hits.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM01109. CUT. 3 hits.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 3 hits.
PROSITEiPS51042. CUT. 3 hits.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiH3BK24_MOUSE
AccessioniPrimary (citable) accession number: H3BK24
Entry historyi
Integrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: February 19, 2014
Last modified: July 6, 2016
This is version 38 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.