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Protein

Glutathione S-transferase kappa

Gene

LOC100186348

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei18NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase kappaUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:LOC100186348Imported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona
Proteomesi
  • UP000008144 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000030897.

Structurei

3D structure databases

ProteinModelPortaliH2XML4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 213DSBAInterPro annotationAdd BLAST204

Sequence similaritiesi

Belongs to the GST superfamily. Kappa family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IJK9. Eukaryota.
COG3917. LUCA.
GeneTreeiENSGT00440000033697.
InParanoidiH2XML4.
KOiK13299.
OMAiETEGFWG.
OrthoDBiEOG091G0LCM.
TreeFamiTF105323.

Family and domain databases

InterProiView protein in InterPro
IPR001853. DSBA-like_thioredoxin_dom.
IPR014440. HCCAis_GSTk.
IPR012336. Thioredoxin-like_fold.
PfamiView protein in Pfam
PF01323. DSBA. 1 hit.
PIRSFiPIRSF006386. HCCAis_GSTk. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

H2XML4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQPMRKILV EFFYDTVSPY SYIAFQVINR CNKSWTNMDL KLKPAFLPAV
60 70 80 90 100
MQQTNNAPPA MVPARGRYMS HDLLRMADFY KVPFKMPRNI SDVMMNKGTI
110 120 130 140 150
SAQRLLTVVA TEAPQYLEGL SREIFMRVWV RDEDVTMVES LKDACRAVGM
160 170 180 190 200
GHEVDQLVGK MAHTDVKDEL RRVTQEAIDY GSFGMPTFVA HLTNEPTMLF
210 220
GSDRLFLLAY YLKQSWPCDV TEAKL
Length:225
Mass (Da):25,809
Last modified:April 18, 2012 - v1
Checksum:i6E181D5F8ECF10F7
GO

Sequence databases

RefSeqiXP_002126524.1. XM_002126488.4.

Genome annotation databases

EnsembliENSCINT00000030749; ENSCINP00000030897; ENSCING00000022634.
GeneIDi100186348.
KEGGicin:100186348.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiH2XML4_CIOIN
AccessioniPrimary (citable) accession number: H2XML4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: June 7, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported