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Protein

Hexokinase

Gene

LOC101071533

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:LOC101071533Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
ProteomesiUP000005226 Componenti: Unplaced

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 2 hexokinase type-1 domains.UniRule annotation
Contains 2 hexokinase type-2 domains.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2UJQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPSLLANC CDELQDDYAQ VDKYLQRFQL SYGDLMEISN RFRREMDKGL
60 70 80 90 100
CRDTNPTAVV KMLPTFVHST PDRTEHGEFL ALDLGGSTFR VLLVKVMADG
110 120 130 140 150
EQKVEMENQI YVIPEHLMKG NGVKLFDHIA DCLANFMEKI GMKEKKLPLG
160 170 180 190 200
FTFSFPCQQT KLDESILLSW TKAFKSNGVE GKDVVSLLRA AIKKRGDFDV
210 220 230 240 250
DVMAVINDTV GAMMTCGYDD QLCEIGLIVG TGTNACYMEQ MRNIEVLDGD
260 270 280 290 300
EGRMCINTEW GAFGDDGTLE DHRTDFDREI DAGSLNPGNQ LFEKMVSGMY
310 320 330 340 350
MGELVRVILV KMTKEQLLFK GKTTVGLLTT GSVKTSYIYT IDNDNDEEGL
360 370 380 390 400
ASAEKVLRGL NLNPTSEDCL AVRRVCQIVS TRSAHLCAAT LVAVLRQIRD
410 420 430 440 450
NKAAEKLRTT IGADGSVYKN HQEFSRRLHK MVRQLMPDSD VRFLTSQCGS
460 470 480 490 500
GKGAAMVTAV AYRYAAQQAE RQAVLNTLRL SRQQLLEVKS RMRERMLQGL
510 520 530 540 550
SKQTHEEASV KMLPTYVIST PNGTEQGDFL VVDLGGSKFR VLLAQIQNGK
560 570 580 590 600
KRNETLHQKI YNIPQETMQG TGKELFDHIV DCIADFLEFM GMSGASLPLG
610 620 630 640 650
FTFSFPCHQS RLDQGILLKW TKGFKASGCE GQDVTMLLKE AVCRRKEFDL
660 670 680 690 700
NFVAVVNDTV GTMMTCGYED PRCEVGLIVG TGTNACYMEE VQNIDLVDGD
710 720 730 740 750
EGRMCVNMEW GAFGDAGELD DFCTQFDAFV DESSTNPGKQ RYEKMVSGMY
760 770 780 790 800
LGEIVRNILM HFTDRGLLFR GKVSERLKMH GIFATKFLSQ IESDRLAMRQ
810 820 830 840 850
VRAILQHLGL TNSTCDDSVL VKEVCGVVSR RAAQLCGAGL AAVVDKMREN
860 870 880 890 900
RNLNQLSVTV GVDGTLYKTH PHFSRIMQET LQDLAPQCQV TFHKSEDGSG
910
KGAALITAVA CRLRREEEQ
Length:919
Mass (Da):102,432
Last modified:March 21, 2012 - v1
Checksum:i2C4D0C2A8EDD2141
GO

Sequence databases

RefSeqiXP_003974607.1. XM_003974558.1.

Genome annotation databases

EnsembliENSTRUT00000037308; ENSTRUP00000037174; ENSTRUG00000014540.
GeneIDi101071533.
KEGGitru:101071533.

Cross-referencesi

Sequence databases

RefSeqiXP_003974607.1. XM_003974558.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTRUT00000037308; ENSTRUP00000037174; ENSTRUG00000014540.
GeneIDi101071533.
KEGGitru:101071533.

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hd-rRImported.
  2. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2UJQ3_TAKRU
AccessioniPrimary (citable) accession number: H2UJQ3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 1, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.