Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Thymidine kinase

Gene

tk1

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tk1Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000033144

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3125 Eukaryota
COG1435 LUCA
GeneTreeiENSGT00390000011309
InParanoidiH2U878
KOiK00857
OMAiCAGLDQD
OrthoDBiEOG091G0HZR
TreeFamiTF314839

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

H2U878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELGGFSKIL PNSPKNARGQ IQVIFGPMFS GKSTELMRRV RRFQLAQYKC
60 70 80 90 100
LVIKYAKDTR YSDSGMATHD KNTMEAVPAN RLGDVHSQAL QVCVIGVDEG
110 120 130 140 150
QFFPDIVEFC EEMANLGKTI IVAALDGTFQ RKPFGSILNL VPLAESVVKL
160 170 180 190 200
NAVCMQCFKE AAYTKRIGAE KEVEVIGGAD KYQAVCRKCY GDLMVDKENR
210 220 230
SPCSDETPPH DHLEKLKDSA VPRKLFSSVI L
Length:231
Mass (Da):25,642
Last modified:March 21, 2012 - v1
Checksum:i4D581E434CF4CB11
GO

Sequence databases

RefSeqiXP_003972121.1, XM_003972072.2

Genome annotation databases

EnsembliENSTRUT00000033270; ENSTRUP00000033144; ENSTRUG00000013060
GeneIDi101063302
KEGGitru:101063302

Similar proteinsi

Entry informationi

Entry nameiH2U878_TAKRU
AccessioniPrimary (citable) accession number: H2U878
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health