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H2U878

- H2U878_TAKRU

UniProt

H2U878 - H2U878_TAKRU

Protein

Thymidine kinase

Gene

LOC101063302

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotation, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:LOC101063302Imported
    OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
    Taxonomic identifieri31033 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPercomorphariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
    ProteomesiUP000005226: Unplaced

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.

    Phylogenomic databases

    GeneTreeiENSGT00390000011309.
    KOiK00857.
    OMAiQILQCSP.
    OrthoDBiEOG7MSMPX.
    TreeFamiTF314839.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2U878-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELGGFSKIL PNSPKNARGQ IQVIFGPMFS GKSTELMRRV RRFQLAQYKC    50
    LVIKYAKDTR YSDSGMATHD KNTMEAVPAN RLGDVHSQAL QVCVIGVDEG 100
    QFFPDIVEFC EEMANLGKTI IVAALDGTFQ RKPFGSILNL VPLAESVVKL 150
    NAVCMQCFKE AAYTKRIGAE KEVEVIGGAD KYQAVCRKCY GDLMVDKENR 200
    SPCSDETPPH DHLEKLKDSA VPRKLFSSVI L 231
    Length:231
    Mass (Da):25,642
    Last modified:March 21, 2012 - v1
    Checksum:i4D581E434CF4CB11
    GO

    Sequence databases

    RefSeqiXP_003972121.1. XM_003972072.1.

    Genome annotation databases

    EnsembliENSTRUT00000033270; ENSTRUP00000033144; ENSTRUG00000013060.
    GeneIDi101063302.
    KEGGitru:101063302.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_003972121.1. XM_003972072.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSTRUT00000033270 ; ENSTRUP00000033144 ; ENSTRUG00000013060 .
    GeneIDi 101063302.
    KEGGi tru:101063302.

    Phylogenomic databases

    GeneTreei ENSGT00390000011309.
    KOi K00857.
    OMAi QILQCSP.
    OrthoDBi EOG7MSMPX.
    TreeFami TF314839.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Hd-rRImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2U878_TAKRU
    AccessioniPrimary (citable) accession number: H2U878
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3