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Protein

Lipase

Gene

LIPN

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei173NucleophileUniRule annotation1
Active sitei344Charge relay systemUniRule annotation1
Active sitei373Charge relay systemUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processLipid degradationUniRule annotation, Lipid metabolism

Protein family/group databases

MEROPSiS33.018.

Names & Taxonomyi

Protein namesi
Recommended name:
LipaseUniRule annotation
Gene namesi
Name:LIPNImported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:7852. LIPN.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500357121919 – 398LipaseSequence analysisAdd BLAST380

Proteomic databases

PaxDbiH2R7L8.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000050554.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 379AB hydrolase-1InterPro annotationAdd BLAST301

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2624. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00550000074328.
InParanoidiH2R7L8.
OMAiMQHALFA.
OrthoDBiEOG091G09AX.
TreeFamiTF315485.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR025483. Lipase_euk.
PfamiView protein in Pfam
PF00561. Abhydrolase_1. 1 hit.
PIRSFiPIRSF000862. Steryl_ester_lip. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

H2R7L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMWLLLTTTC LICGTLNAGG FLDLENEVNP EVWMNTSEII IYNGYPSEEY
60 70 80 90 100
EVTTEDGYIL LVNRIPYGRR HARSTGARPV VYMQHALFAD NAYWLENYAN
110 120 130 140 150
GSLGFLLADA GYDVWMGNSR GNTWSRRHKT LSETDEKFWA FSFDEMAKYD
160 170 180 190 200
LPGVIDFIVN KTGQEKLYFI GHSLGTTIGF VAFSTMPELA QRIKMNFALG
210 220 230 240 250
PTISFKYPTG IFTRFFLLPN SIIKAVFGTK GFFLEDKKTK IASTKICNNK
260 270 280 290 300
ILWLICSEFM SLWAGSNKKN MNQSRMDVYM SHAPTGSSVQ NILHIKQLYQ
310 320 330 340 350
SDEFRAYDWG NEADNMKHYN QSHPPIYDLT AMKVPTAIWA GGHDVLVTPQ
360 370 380 390
DVARILPQIK SLHYFKLLPD WNHFDFVWGL DAPQRMYSEI IALMKAYS
Length:398
Mass (Da):45,559
Last modified:March 21, 2012 - v1
Checksum:iD9BBEA06D9C7CABD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04051032 Genomic DNA. No translation available.
RefSeqiXP_521546.3. XM_521546.4.

Genome annotation databases

EnsembliENSPTRT00000057644; ENSPTRP00000050554; ENSPTRG00000029842.
GeneIDi466144.
KEGGiptr:466144.

Similar proteinsi

Entry informationi

Entry nameiH2R7L8_PANTR
AccessioniPrimary (citable) accession number: H2R7L8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported